What should I Know Regarding Pregnancy, Nursing and Administering Zyban to Children or the Elderly?
If you are PREGNANT
- FDB Only When Necessary: AVAILABLE HUMAN DATA SUGGEST DEVELOPMENTAL TOXICITY RISK IS LOW.
If you are NURSING
- Precaution: INSUFFICIENT HUMAN DATA; LOW LEVELS EXCRETED IN BREAST MILK
If you are an adult over 60
- management or monitoring precaution: Hepatic-Lower doses are generally recommended in elderly. Bupropion is extensively metabolized to active metabolites, and the elderly may accumulate drug. Renal-Possible accumulation of active metabolites. Consider lower dose for GFR<90 mL/min and monitoring renal function. Neuro/Psych-Consider bupropion CNS side effects of dizziness, somnolence and memory loss when using in the elderly.
Giving Zyban to a child under 12
- Severe Precaution: Possible increased suicidal ideation and attempt with underlying major depression. No safety and efficacy established.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.