How to use Bavencio Vial
This medication is given by a health care professional. It is injected slowly into a vein over 60 minutes. It is given as directed by your doctor, usually once every 2 weeks.
Infusion reactions may happen while you are receiving avelumab. Your doctor may prescribe other medications (such as diphenhydramine, acetaminophen) before treatment to help prevent these side effects. Tell your doctor right away if you have any symptoms of infusion reactions such as flushing, trouble breathing, fever, chills, hives, abdominal/back pain, or dizziness.
The dosage is based on your medical condition and response to treatment. Your doctor may stop your treatment for some time if you get serious side effects. Your doctor may also prescribe another medication (a corticosteroid such as prednisone) to help treat side effects of this medication.
To get the most benefit, do not miss any doses. To help you remember, mark the days on the calendar when you need to receive this medication.
See also How to Use section.
People using this medication may have serious side effects. However, you have been prescribed this drug because your doctor has judged that the benefit to you is greater than the risk of side effects. Careful monitoring by your doctor may decrease your risk.
Tell your doctor right away if you have any serious side effects, including: new/worsening cough, diarrhea with blood/mucus, mouth/throat sores, severe stomach/abdominal pain, symptoms of liver disease (such as nausea/vomiting that doesn't stop, loss of appetite, yellowing eyes/skin, dark urine), signs of kidney problems (such as change in the amount of urine, pink/bloody urine), easy bruising/bleeding, swelling hands/ankles/feet, unusual weakness, joint stiffness/pain, muscle weakness/pain, numbness/tingling of arms/legs, eye redness/pain, sensitivity to light, vision changes.
Avelumab may cause hormone gland problems (such as thyroid, pituitary, adrenal, pancreas). Your body could make too much or too little hormone. Tell your doctor right away if you have any symptoms such as: cold or heat intolerance, unexplained weight loss/gain, increased thirst/urination, mood or behavior changes (such as decreased sex drive, irritability, forgetfulness), slow/fast/pounding/irregular heartbeat, unusual tiredness, constipation.
Get medical help right away if you have any very serious side effects, including: chest pain, shortness of breath.
Avelumab can commonly cause itching or a rash that is usually not serious. However, you may not be able to tell it apart from a rare rash that could be a sign of a severe reaction. Get medical help right away if you develop any rash or itching.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: fever, swollen lymph nodes, rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Before using avelumab, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This drug may make you dizzy. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).
Tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while using avelumab. Avelumab may harm an unborn baby. Ask about reliable forms of birth control while using this medication and for 1 month after stopping treatment. If you become pregnant, talk to your doctor right away about the risks and benefits of this medication.
It is unknown if this drug passes into breast milk. Because of the possible risk to the infant, breast-feeding is not recommended while using this drug and for 1 month after stopping treatment. Consult your doctor before breast-feeding.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.
Not applicable. This medication is given in a hospital or clinic and will not be stored at home.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.