This medication is used to lower the risk of death in people with a certain rare condition (Hutchinson-Gilford Progeria Syndrome - HGPS). It is also used to treat people with certain other rare conditions (Progeroid Laminopathies). Lonafarnib works by decreasing the amount of a harmful substance (progerin) caused by these conditions.

How to use Zokinvy 75 Mg Capsule Progeria Syndrome Treatment Agents

Read the Patient Information Leaflet and Instructions for Use if available from your pharmacist before you start using lonafarnib and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth as directed by your doctor, usually twice a day: once with the morning meal and once with the evening meal. Swallow the capsules whole with water. Do not crush or chew.

If you have trouble swallowing the capsule, it may be opened and the contents mixed as directed in orange juice, applesauce, or certain liquids used to make a suspension. Swallow the mixture within 10 minutes of mixing it. Do not save the mixture for future use.

Avoid eating grapefruit or Seville oranges or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely. Do not mix the contents of the capsule in juice containing grapefruit or Seville oranges. Grapefruit and Seville oranges can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details.

The dosage is based on your medical condition, body size, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.

Do not increase your dose or use this drug more often than prescribed. Your condition will not improve any faster, and your risk of serious side effects will increase.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.