How to use
Read the Patient Information Leaflet if available from your pharmacist before you start using infigratinib and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take this medication by mouth on an empty stomach at least 1 hour before or 2 hours after food as directed by your doctor, usually once daily for 21 days, then stopping the medication for 7 days. This is one cycle of treatment. Continue taking the medication this way as directed by your doctor.
Swallow the capsule whole. Do not crush, chew, or dissolve the capsules. Take it with a full glass of water (8 ounces/240 milliliters) unless your doctor directs you otherwise.
Avoid certain drugs that reduce stomach acid/heartburn (proton pump inhibitors-PPIs such as lansoprazole, omeprazole) during treatment with infigratinib. If you are taking certain other drugs that reduce stomach acid/heartburn (H2 blockers such as famotidine, ranitidine), take infigratinib at least 2 hours before or 10 hours after taking an H2 blocker. If you are taking antacids, take infigratinib at least 2 hours before or after taking an antacid.
Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely. Grapefruit can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details.
The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). If you have certain side effects, your doctor may adjust your dose or stop treatment for some time.
Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of serious side effects will increase.
If you vomit your dose of infigratinib, do not take another dose. Take your next dose at your regular scheduled time. Do not take two doses at the same time.
Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day on the days that you are scheduled to take the medication.
Since this drug can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the capsules.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.