Warnings:

Levoketoconazole has rarely caused very serious (possibly fatal) liver problems. It should not be used by people with severe liver disease, gallstones, or by people who had liver problems caused by azole antifungal drugs (such as ketoconazole). Get medical help right away if you develop symptoms of liver problems, such as nausea/vomiting that doesn't stop, loss of appetite, stomach/abdominal pain, yellowing eyes/skin, dark urine.

Levoketoconazole may also cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away. Levoketoconazole must not be used with other medications that may also affect the heart rhythm (QT prolongation) or be used by people with a history of certain heart diseases (such as ventricular arrhythmias, long QT syndrome). Tell your doctor and pharmacist about all the medications and products you take before you start levoketoconazole treatment. See also Precautions and Drug Interactions sections.

To reduce the risk of these very serious side effects, your doctor should order tests (such as liver function, EKG) before you start this medication and while you are taking it.

Warnings:

Levoketoconazole has rarely caused very serious (possibly fatal) liver problems. It should not be used by people with severe liver disease, gallstones, or by people who had liver problems caused by azole antifungal drugs (such as ketoconazole). Get medical help right away if you develop symptoms of liver problems, such as nausea/vomiting that doesn't stop, loss of appetite, stomach/abdominal pain, yellowing eyes/skin, dark urine.

Levoketoconazole may also cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away. Levoketoconazole must not be used with other medications that may also affect the heart rhythm (QT prolongation) or be used by people with a history of certain heart diseases (such as ventricular arrhythmias, long QT syndrome). Tell your doctor and pharmacist about all the medications and products you take before you start levoketoconazole treatment. See also Precautions and Drug Interactions sections.

To reduce the risk of these very serious side effects, your doctor should order tests (such as liver function, EKG) before you start this medication and while you are taking it.

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Uses

This medication is used to treat high levels of a certain hormone (cortisol) in people with Cushing's syndrome. Levoketoconazole works by decreasing the amount of cortisol made by the body.

How to use

Read the Medication Guide provided by your pharmacist before you start taking levoketoconazole and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor, usually twice a day. The dosage is based on your medical condition, lab tests, and response to treatment.

If you are taking an antacid, take levoketoconazole at least 2 hours before taking the antacid, or levoketoconazole may not be absorbed into the body. See also Drug Interactions section for more information.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.

Tell your doctor if your condition does not get better or if it gets worse.

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.