DACTINOMYCIN Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • low blood counts due to bone marrow failure
  • anemia
  • decreased blood platelets
  • low levels of a type of white blood cell called neutrophils
  • canker sores
  • inflammation of the esophagus
  • inflammation of the rectum
  • abnormal liver function tests

If experienced, these tend to have a Less Severe expression i

  • stomatitis, a condition with painful swelling and sores inside the mouth
  • hair loss
  • acne
  • fever
  • low energy
  • a skin rash
  • nausea
  • vomiting
  • difficulty swallowing

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • low levels of white blood cells
  • stomach or intestinal ulcer
  • inflammation of the liver called hepatitis

If experienced, these tend to have a Less Severe expression i

  • decreased appetite
  • diarrhea
  • intense abdominal pain

RARE side effects

If experienced, these tend to have a Severe expression i

  • an infection
  • low amount of calcium in the blood
  • a type of blood disorder with a decrease in all types of blood cells called pancytopenia
  • a type of blood clotting disorder called disseminated intravascular coagulation
  • optic neuropathy, a disease of the optic nerve
  • thrombophlebitis, an inflamed vein due to a blood clot
  • hepatic veno-occlusive disease, a type of liver disease
  • bleeding
  • the presence of air or gas in the lung
  • a type of inflammation of the lung called interstitial pneumonitis
  • bronchospasm
  • acute liver failure
  • kidney failure
  • decreased kidney function
  • erythema multiforme, a type of allergic skin reaction
  • a skin disorder with blistering and peeling skin called toxic epidermal necrolysis
  • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
  • erythema or redness of skin or mucous membrane
  • an enlarged liver
  • ascites
  • a significant type of allergic reaction called anaphylaxis
  • a hypersensitivity reaction to a drug
  • reactions at the site of the injection
  • damage to the skin and tissue around the injection site
  • a yellowing of the eyes or skin from buildup of bilirubin called jaundice
  • sepsis
  • radiation recall syndrome
  • tumor lysis syndrome

If experienced, these tend to have a Less Severe expression i

  • inflammation of the lips
  • constipation
  • skin inflammation
  • skin discoloration
  • muscle pain
  • a feeling of general discomfort called malaise
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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.