MITOXANTRONE HCL Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • an infection
  • low levels of white blood cells
  • stomatitis, a condition with painful swelling and sores inside the mouth
  • bleeding of the stomach or intestines
  • trouble breathing
  • cough
  • stomach cramps

If experienced, these tend to have a Less Severe expression i

  • throat irritation
  • a common cold
  • a stuffy and runny nose
  • urinary tract infection
  • absence of menstrual periods
  • a problem with menstrual periods
  • hair loss
  • headache
  • nausea
  • vomiting
  • diarrhea
  • abnormal color of urine
  • generalized weakness

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • decreased blood platelets
  • pink eye
  • abnormal heart rhythm
  • chronic heart failure
  • kidney failure
  • seizures
  • a yellowing of the eyes or skin from buildup of bilirubin called jaundice

If experienced, these tend to have a Less Severe expression i

  • anemia
  • inflammation of the tissue lining the sinuses
  • backache
  • bluish discoloration of the white outer coat of the eye

RARE side effects

If experienced, these tend to have a Severe expression i

  • abnormal heart electrical signals
  • left ventricular heart failure
  • low blood pressure
  • a type of inflammation of the lung called interstitial pneumonitis
  • hives
  • a skin rash
  • a significant type of allergic reaction called anaphylaxis
  • reactions at the site of the injection
  • a significant drop in a certain type of white blood cell called a neutrophil
  • therapy-related acute myeloid leukemia
  • inflammation of the vein, or phlebitis after infusion

If experienced, these tend to have a Less Severe expression i

  • bone pain
  • chest pain
  • fast heartbeat
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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.