If you are:
Absolute Contraindication: INSUFFICIENT HUMAN DATA; POTENTIAL FOR SEVERE TOXICITY
An adult over 60:
management or monitoring precaution: General-Assess bone marrow reserves in the elderly as they may be lower, thus increasing the risk of prolonged suppression. Cardiovascular-Cardiotoxicity may be more frequent in elderly. Renal-age-related renal dysfunction may require dose reduction.
Giving daunorubicin HCL Vial to a child under 12:
Severe Precaution: Risk of cardiotoxicity above cumulative dose 300 mg/m2
Severe Precaution: Risk of cardiotoxicity above cumulative dose 10 mg/kg