Spironolactone Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • high levels of potassium in the blood
  • If experienced, these tend to have a Less Severe expression i

  • irritation of the stomach or intestines
  • INFREQUENT side effects

    If experienced, these tend to have a Severe expression i

  • low amount of magnesium in the blood
  • low amount of sodium in the blood
  • If experienced, these tend to have a Less Severe expression i

  • abnormal sexual function
  • the inability to have an erection
  • enlarged breasts
  • dizziness
  • headache
  • RARE side effects

    If experienced, these tend to have a Severe expression i

  • low amount of calcium in the blood
  • dehydration
  • decreased blood platelets
  • very low levels of granulocytes, a type of white blood cell
  • low levels of white blood cells
  • increased eosinophils in the blood
  • allergic reaction causing inflammation of blood vessels
  • inflammation of the blood vessels
  • low blood pressure
  • a stomach ulcer
  • bleeding of the stomach or intestines
  • decreased kidney function
  • a skin disorder with blistering and peeling skin called toxic epidermal necrolysis
  • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
  • trouble breathing
  • high amount of uric acid in the blood
  • high blood sugar
  • a significant type of allergic reaction called anaphylaxis
  • inflammation of the liver with stoppage of bile flow
  • decreased blood volume
  • acid base problem with low chloride and basic pH blood
  • a type of significant allergic skin reaction called DRESS syndrome
  • If experienced, these tend to have a Less Severe expression i

  • confusion
  • altered interest in having sexual intercourse
  • a type of stomach irritation called gastritis
  • breast pain
  • absence of menstrual periods
  • irregular periods
  • a problem with menstrual periods
  • hair loss
  • leg cramps
  • drowsiness
  • fever
  • loss of muscle coordination
  • nausea
  • vomiting
  • diarrhea
  • stomach cramps
  • low energy and weakness
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    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.