Does Lexapro Interact with other Medications?

Severe Interactions

These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • SEROTONIN REUPTAKE INHIBITORS; SNRIS/SELECTED MAOIS
  • QT PROLONGING AGENTS/LEVOKETOCONAZOLE
  • QT PROLONGING AGENTS/HYDROXYCHLOROQUINE
  • SLT STRONG & MOD CYP2D6 INHIBIT THAT PROLONG QT/THIORIDAZINE
  • QT PROLONGING AGENTS/ANAGRELIDE
  • SEROTONINERGIC AGENTS/DAPOXETINE
  • QT PROLONGING AGENTS/DOMPERIDONE
  • QT PROLONGING AGENTS/DRONEDARONE
  • QT PROLONGING AGENTS/ARTEMETHER-LUMEFANTRINE
  • QT PROLONGING AGENTS/DISOPYRAMIDE
  • QT PROLONGING AGENTS/CISAPRIDE
  • QT PROLONGING AGENTS/SERTINDOLE
  • QT PROLONGING AGENTS/DROPERIDOL
  • QT PROLONGING AGENTS/LEVOMETHADYL
  • QT PROLONGING AGENTS/SPARFLOXACIN
  • QT PROLONGING AGENTS/HALOFANTRINE
  • SELECTED QT PROLONGING AGENTS/ZIPRASIDONE
  • QT PROLONGING AGENTS/BEPRIDIL
  • SSRIS; NEFAZODONE/PIMOZIDE
  • SEROTONINERGIC AGENTS/SIBUTRAMINE
  • Serious Interactions

    These medications may interact and cause very harmful effects. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • SEROTONIN REUPTAKE INHIBITORS/LINEZOLID
  • CITALOPRAM; ESCITALOPRAM/CILOSTAZOL
  • CITALOPRAM (>20 MG); ESCITALOPRAM (>15 MG)/TICLOPIDINE
  • CITALOPRAM; ESCITALOPRAM/FLUCONAZOLE
  • QT PROLONGING AGENTS/PACRITINIB
  • QT PROLONGING AGENTS/PANOBINOSTAT
  • QT PROLONGING AGENTS/MOBOCERTINIB
  • QT PROLONGING AGENTS/FEXINIDAZOLE
  • QT PROLONGING AGENTS/LEVOMEPROMAZINE
  • QT PROLONGING AGENTS/PAZOPANIB
  • QT PROLONGING AGENTS/SELPERCATINIB
  • QT PROLONGING AGENTS/OXALIPLATIN
  • QT PROLONGING AGENTS/LEFAMULIN
  • QT PROLONGING AGENTS/ENTRECTINIB
  • QT PROLONGING AGENTS/GLASDEGIB
  • AGENTS THAT AFFECT CATECHOLAMINES/IOBENGUANE I 123
  • AGENTS THAT AFFECT CATECHOLAMINES/IOBENGUANE I 131
  • QT PROLONGING AGENTS/IVOSIDENIB
  • QT PROLONGING AGENTS/ENCORAFENIB
  • QT PROLONGING AGENTS/LOFEXIDINE
  • QT PROLONGING AGENTS/MACIMORELIN
  • QT PROLONGING AGENTS/INOTUZUMAB OZOGAMICIN
  • QT PROLONGING AGENTS/RIBOCICLIB
  • QT PROLONGING AGENTS/HYDROXYZINE
  • QT PROLONGING AGENTS/PIMAVANSERIN
  • QT PROLONGING AGENTS/VEMURAFENIB
  • QT PROLONGING AGENTS/TELAVANCIN
  • QT PROLONGING AGENTS/SORAFENIB
  • QT PROLONGING AGENTS/ROMIDEPSIN
  • QT PROLONGING AGENTS/ONDANSETRON
  • QT PROLONGING AGENTS/LEVOMETHADONE; METHADONE
  • QT PROLONGING AGENTS/LENVATINIB
  • QT PROLONGING AGENTS/GADOFOSVESET
  • QT PROLONGING AGENTS/EZOGABINE
  • QT PROLONGING AGENTS/CRIZOTINIB
  • QT PROLONGING AGENTS/CERITINIB
  • QT PROLONGING AGENTS/BEDAQUILINE
  • QT PROLONGING AGENTS/ARSENIC
  • QT PROLONGING AGENTS/SULPIRIDE
  • QT PROLONGING AGENTS/PROPOFOL
  • QT PROLONGING AGENTS/PENTAMIDINE
  • QT PROLONGING AGENTS/ERYTHROMYCIN
  • QT PROLONGING AGENTS/DONEPEZIL
  • QT PROLONGING AGENTS/CHLORPROMAZINE
  • QT PROLONGING AGENTS/CHLOROQUINE
  • QT PROLONGING AGENTS/AZITHROMYCIN
  • QT PROLONGING AGENTS/SOTALOL
  • QT PROLONGING AGENTS/PROCAINAMIDE
  • QT PROLONGING AGENTS/IBUTILIDE
  • QT PROLONGING AGENTS/HYDROQUINIDINE; QUINIDINE
  • QT PROLONGING AGENTS/FLECAINIDE
  • QT PROLONGING AGENTS/DELAMANID
  • STRONG & MODERATE CYP2D6 INHIBITORS/ELIGLUSTAT
  • QT PROLONGING AGENTS/CITALOPRAM
  • CLOMIPRAMINE; IMIPRAMINE; SSRIS; SNRIS;/MEPERIDINE
  • QT PROLONGING AGENTS/DOFETILIDE
  • QT PROLONGING AGENTS/QUETIAPINE
  • DOPAMINE TRANSPORTER BINDERS/IOFLUPANE I 123
  • QT PROLONGING AGENTS/VANDETANIB
  • QT PROLONGING AGENTS/SAQUINAVIR
  • QT PROLONGING AGENTS/ILOPERIDONE
  • QT PROLONGING AGENTS/LOPINAVIR
  • QT PROLONGING AGENTS/TOREMIFENE
  • SSRIS; SNRIS/METOCLOPRAMIDE
  • QT PROLONGING AGENTS/ZUCLOPENTHIXOL
  • QT PROLONGING AGENTS/NILOTINIB
  • QT PROLONGING AGENTS/PALIPERIDONE
  • QT PROLONGING AGENTS/IVABRADINE
  • QT PROLONGING AGENTS/AMIODARONE
  • QT PROLONGING AGENTS/MESORIDAZINE
  • SSRIS; SNRIS/SELECTED ANTICOAGULANTS (VITAMIN K ANTAGONISTS)
  • Moderate Interactions

    These medications may cause some risk when taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • SSRIS; SNRIS/SELECTED NSAIDS; ASPIRIN
  • SSRIS;SNRIS/SLT ANTICOAGULANTS;ANTIPLATELETS;THROMBOLYTICS
  • SELECTED SSRIS; SNRIS/CLOPIDOGREL
  • ESCITALOPRAM/BOCEPREVIR; TELAPREVIR
  • SELECT SEROTONERGIC AGENTS/FENTANYL
  • ESCITALOPRAM (> 15 MG)/SELECTED CYP2C19 INHIBITORS
  • ESCITALOPRAM/QT PROLONGING AGENTS
  • ESCITALOPRAM (<= 15 MG)/SELECTED CYP2C19 INHIBITORS
  • SSRIS; VILAZODONE/FLURBIPROFEN
  • SSRIS; VILAZODONE/SELECTED NSAIDS
  • CITALOPRAM (<= 20 MG); ESCITALOPRAM (<= 15 MG)/TICLOPIDINE
  • SELECTED SSRIS; SELECTED SNRIS/CLOMIPRAMINE; IMIPRAMINE
  • CITALOPRAM; ESCITALOPRAM/SLT DUAL CYP2C19 & CYP3A4 INDUCERS
  • CITALOPRAM;ESCITALOPRAM/SLT 2C19&3A4 INDUCER THAT PROLONG QT
  • ESCITALOPRAM (> 15 MG)/SLT CYP2C19 INHIB THAT PROLONG QT
  • ESCITALOPRAM (<= 15 MG)/SLT CYP2C19 INHIB THAT PROLONG QT
  • QT PROLONGING AGENTS/SAVOLITINIB
  • QT PROLONGING AGENTS/TOLTERODINE
  • QT PROLONGING AGENTS/OZANIMOD
  • QT PROLONGING AGENTS/PONESIMOD
  • QT PROLONGING AGENTS/SIPONIMOD
  • QT PROLONGING AGENTS/GALANTAMINE
  • SELECTED WEAK CYP2D6 INHIBITORS/TAMOXIFEN
  • QT PROLONGING AGENTS/AMISULPRIDE
  • SELECTED SSRIS; SNRIS/CYCLOBENZAPRINE
  • QT PROLONGING AGENTS/PITOLISANT
  • SELECTED CYP2D6 INHIBITORS/METOPROLOL
  • SNRIS; SSRIS/BUPROPION
  • QT PROLONGING AGENTS/GILTERITINIB
  • AGENTS WITH HYPONATREMIA RISK/DESMOPRESSIN
  • AGENTS WITH HYPONATREMIA RISK/DESMOPRESSIN (NOCTURIA)
  • QT PROLONGING AGENTS/ERIBULIN
  • MODERATE CYP2D6 INHIBITORS/BREXPIPRAZOLE
  • QT PROLONGING AGENTS/CLARITHROMYCIN
  • QT PROLONGING AGENTS/SEVOFLURANE
  • QT PROLONGING AGENTS/FINGOLIMOD
  • SELECTED MODERATE TO STRONG CYP2D6 INHIBITORS/TRAMADOL
  • QT PROLONGING AGENTS/CIPROFLOXACIN
  • QT PROLONGING AGENTS/POSACONAZOLE
  • QT PROLONGING AGENTS/RANOLAZINE
  • SSRIS; SNRIS/AMPHETAMINES; PHENTERMINE
  • SELECTED SSRIS/PERHEXILINE
  • SSRIS; SNRIS/TAPENTADOL
  • CITALOPRAM; ESCITALOPRAM/CLOZAPINE
  • SEROTONINERGIC AGENTS/DEXFENFLURAMINE; FENFLURAMINE
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    Drug Survey

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    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.