HUMIRA Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • an infection
  • dehydration
  • a common cold
  • a condition with symptoms that resemble lupus
  • a skin rash

If experienced, these tend to have a Less Severe expression i

  • throat irritation
  • itching
  • headache
  • nausea

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • erysipelas, a bacterial skin infection
  • shingles
  • an infection due to a fungus
  • pseudohypoparathyroidism
  • monoclonal gammopathy, a condition with abnormal proteins in the blood
  • an excess of ketones in the body
  • very low levels of granulocytes, a type of white blood cell
  • low levels of white blood cells
  • acquired increase of red blood cells
  • multiple sclerosis
  • clouding of the lens of the eye called cataracts
  • high blood pressure
  • extremely high blood pressure
  • a heart attack
  • inflammation of the covering of the heart or pericardium
  • fluid in the covering of the heart or pericardium
  • atrial fibrillation
  • complete stoppage of the heart
  • abnormal heart rhythm
  • chronic heart failure
  • subdural intracranial hemorrhage
  • formation of blood clots in the leg veins
  • pneumonia
  • asthma
  • bronchospasm
  • liver tissue death
  • gallstones
  • bleeding of the stomach or intestines
  • pyelonephritis, infection and inflammation of the kidney and renal pelvis
  • kidney stones
  • inflammation of the bladder
  • urinary tract infection
  • fainting
  • flu-like symptoms
  • fluid retention in the legs, feet, arms or hands
  • heart throbbing or pounding
  • trouble breathing
  • chest pain
  • abnormal liver function tests
  • a broken bone
  • reactivation of a past tuberculosis infection
  • malignant lymphoma
  • abnormal increase in red blood cells
  • osteonecrosis, the death of bone tissue due to a lack of blood supply
  • an accidental injury
  • fast heartbeat

If experienced, these tend to have a Less Severe expression i

  • confusion
  • escape of fluid into the lungs
  • inflammation of the esophagus
  • inflammation of the lining of the stomach and intestines
  • bacteria causing an infection in the joints
  • arthritis
  • backache
  • muscle weakness
  • pain in the arms or legs
  • cramps
  • muscle tremors
  • vomiting
  • pelvic pain
  • impaired wound healing
  • a feeling of pins and needles on skin
  • inflammation of the lining of a joint
  • intense abdominal pain
  • injection site erythema

RARE side effects

If experienced, these tend to have a Severe expression i

  • active tuberculosis
  • an infection by the bacteria Listeria monocytogenes
  • a systemic inflammatory response called sepsis due to an infection with bacteria
  • a type of systemic fungal infection called coccidioidomycosis
  • a type of fungal lung infection called histoplasmosis
  • an infection by the fungus Blastomyces dermatitidis
  • opportunistic fungal infection
  • sarcoidosis
  • an infection due to a protozoa organism
  • malignant melanoma, a type of skin cancer
  • cancer or malignancy
  • leukemia
  • squamous cell carcinoma
  • a type of blood disorder with a decrease in all types of blood cells called pancytopenia
  • low blood counts due to bone marrow failure
  • decreased blood platelets
  • demyelination, a type of nervous system disorder
  • Guillain-Barre syndrome
  • sudden blindness and pain upon moving the eye
  • a clot in the lung
  • heart failure
  • a stroke
  • inflammation of the blood vessels
  • inflammation of blood vessels in the skin
  • blood clot in a deep vein of the extremities
  • a type of lung infection called Legionnaires' disease
  • a condition where there is formation of fibrous tissue in the lung called pulmonary fibrosis
  • appendicitis
  • diverticulitis
  • a hole in the intestine
  • liver inflammation resulting from an abnormal immune response
  • liver failure
  • inflammation of the liver called hepatitis
  • inflammation of the gallbladder
  • erythema multiforme, a type of allergic skin reaction
  • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
  • a significant type of allergic reaction called anaphylaxis
  • a type of allergic reaction called angioedema
  • basal cell carcinoma of the skin
  • reactivation of hepatitis B infection
  • drug therapy that worsens or flares psoriasis
  • pancreatitis
  • hepatosplenic T-cell lymphoma
  • worsening of chronic heart failure
  • cellulitis
  • a type of skin cancer called Merkel cell carcinoma

If experienced, these tend to have a Less Severe expression i

  • a problem with menstrual periods
  • hair loss

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.