If you are:
Only When Necessary:
Precaution: DRUG EXCRETED IN MOUSE STUDIES, INSUFF. HUMAN DATA AVAILABLE.
An adult over 60:
management or monitoring precaution: Urogenital-Highly anticholinergic; pre-existing urinary retention is contraindicated. Neuro/Psych-May predispose to sedation, confusion and falls. High risk of delirium. Gastrointestinal-Risk for worsening or new-onset constipation. Hepatic-Lower doses are recommended in severe impairment. Renal-CrCL=10-30 mL/min. affects drug disposition; lower doses recommended. Cardiovascular-Heart failure, bradyarrhythmias, hypomagnesemia, hypokalemia may increase the risk of QT prolongation.
Giving Detrol to a child under 12:
Severe Precaution: Efficacy not established. Aggression, abnormal and hyperactive behavior reported. Increased risk of urinary tract infections,