Quinolones/Dairy Products Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug, changing your diet or commencing any course of treatment.

Medical warning:

Very important. A change in your diet, medicine, or dosage may be necessary. Promptly consult your doctor or pharmacist.

How the interaction occurs:

When dairy products are taken with this medicine, they may bind to this medicine and interfere with its absorption into your bloodstream. Not all quinolone-type antibiotics interact with dairy products.

What might happen:

A decrease in the beneficial effects of this medicine may occur.

What you should do about this interaction:

Avoid taking this medicine with milk or other dairy products (see list below). Eat or drink dairy products as far apart from your dose of this medicine as possible. Contact your healthcare professional (e.g., doctor or pharmacist) for more information and recommendations for your specific medicine. The following is a list of dairy foods: milk, cream, yogurt, cheese (all), ice cream, sherbets (some have milk or cream).Your healthcare professionals may be aware of this interaction and may be monitoring you for it. Do not start, stop, or change your medicine or diet before checking with them first.

  • 1.Neuvonen PJ, Kivisto KT, Lehto P. Interference of dairy products with the absorption of ciprofloxacin. Clin Pharmacol Ther 1991 Nov;50(5 Pt 1):498-502.
  • 2.Kivisto KT, Ojala-Karlsson P, Neuvonen PJ. Inhibition of norfloxacin absorption by dairy products. Antimicrob Agents Chemother 1992 Feb; 36(2):489-91.
  • 3.Minami R, Inotsume N, Nakano M, Sudo Y, Higashi A, Matsuda I. Effect of milk on absorption of norfloxacin in healthy volunteers. J Clin Pharmacol 1993 Dec;33(12):1238-40.
  • 4.Marchbanks CR. Drug-drug interactions with fluoroquinolones. Pharmacotherapy 1993 Mar-Apr;13(2 Pt 2):23S-28S.
  • 5.Brouwers JR. Drug interactions with quinolone antibacterials. Drug Saf 1992 Jul-Aug;7(4):268-81.
  • 6.Raxar (grepafloxacin) US prescribing information. Glaxo-Wellcome 1997.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.