Estradiol-Levonorgestrel Patch, Transdermal Weekly Side Effects by Likelihood and Severity

COMMON side effects


If experienced, these tend to have a Severe expression

  • Abnormally Long Or Heavy Periods
  • Absence Of Menstrual Periods
  • Bleeding Not Related To Menstrual Period
  • High Blood Sugar

If experienced, these tend to have a Less Severe expression

  • A Decrease In How Often A Woman Menstruates
  • Abdominal Bloating
  • An Ovarian Cyst
  • Bleeding Not Related To Menstrual Period
  • Breast Pain
  • Diarrhea
  • Dizziness
  • Enlargement Of An Ovary
  • Fluid Retention In The Legs, Feet, Arms Or Hands
  • Headache
  • Itching
  • Low Energy
  • Mood Changes
  • Nausea
  • Nervousness
  • Stomach Cramps
  • Throat Irritation
  • Visible Water Retention
  • Vomiting
  • Weight Gain

INFREQUENT side effects


If experienced, these tend to have a Severe expression

  • A Common Cold
  • A Skin Rash
  • Breastmilk Production Not Associated With Childbirth Or Nursing
  • Depression
  • Inflammation Of The Lining Of The Stomach And Intestines

If experienced, these tend to have a Less Severe expression

  • A Migraine Headache
  • A Yeast Infection Of The Vagina And Vulva
  • Acne
  • Altered Interest In Having Sexual Intercourse
  • Backache
  • Breast Pain
  • Bronchitis
  • Constipation
  • Difficulty Sleeping
  • Discharge Of Fluid From The Cervix
  • Dizziness
  • Drug-Induced Hot Flashes
  • Hair Loss
  • Headache
  • Hirsutism, A Condition Of Hair Growth On Parts Of The Body Normally Without Hair
  • Inflammation Or Infection Of The Vagina
  • Nausea
  • Neck Pain
  • Skin Irritation
  • Vomiting
  • Yellow-Brown Patches On Skin

RARE side effects


If experienced, these tend to have a Severe expression

  • A Blockage In The Gallbladder
  • A Blockage Of The Bile Duct That Resulting In High Bilirubin Levels
  • A Breast Tumor
  • A Clot In The Lung
  • A Clot In The Small Veins That Carry Blood To Or From The Retina Of The Eye
  • A Heart Attack
  • A Significant Type Of Allergic Reaction Called Anaphylaxis
  • A Stroke
  • A Type Of Allergic Reaction Called Angioedema
  • Acute Inflammation Of The Pancreas
  • An Epithelial Cancer Of The Ovary
  • Angina, A Type Of Chest Pain
  • Blood Clot In A Deep Vein Of The Extremities
  • Cancer In The Lining Of The Uterus
  • Cancer Of The Ovary
  • Dementia
  • Erythema Multiforme, A Type Of Allergic Skin Reaction
  • Erythema Nodosum, A Skin Condition With Red And Painful Nodules
  • Fluid Secretion From The Breast
  • High Amount Of Triglyceride In The Blood
  • Inflammation Of The Liver Called Hepatitis
  • Irregular Involuntary Spasms Of Limbs Or Facial Muscles
  • Large Purple Or Brown Skin Blotches
  • Low Amount Of Calcium In The Blood
  • Non-Cancerous Cysts Causing The Breast To Feel Lumpy
  • Obstruction Of A Blood Vessel By A Blood Clot
  • Overgrowth Of The Uterine Lining
  • Throat Swelling
  • Ventricular Premature Beats

If experienced, these tend to have a Less Severe expression

  • A Disorder Of The Fallopian Tube
  • A Feeling Of General Discomfort Called Malaise
  • A Feeling Of Pins And Needles On Skin
  • A Skin Rash
  • Abnormally Long Or Heavy Periods
  • Absence Of Menstrual Periods
  • An Ovarian Cyst
  • Breastmilk Production Not Associated With Childbirth Or Nursing
  • Darkening Of The Skin
  • Depression
  • Diarrhea
  • Difficulty Sleeping
  • Dry Skin
  • Enlarged Breasts
  • Enlarged Superficial Veins
  • Erythema Or Skin Redness
  • Fast Heartbeat
  • Flu-Like Symptoms
  • Gas
  • Generalized Weakness
  • Hair Loss
  • Heart Throbbing Or Pounding
  • High Blood Pressure
  • Hirsutism, A Condition Of Hair Growth On Parts Of The Body Normally Without Hair
  • Hives
  • Indigestion
  • Irritability
  • Joint Pain
  • Leg Cramps
  • Low Energy
  • Mood Changes
  • Muscle Spasm
  • Nervousness
  • Pain With Menstruation
  • Pelvic Pain
  • Reduced Sensation In The Mouth
  • Sensation Of Spinning Or Whirling
  • Swelling Of The Tongue
  • Trouble Breathing
  • Uterine Cramps
  • Uterine Fibroids
  • Vaginal Discharge
  • Water Retention
  • Yellow-Brown Patches On Skin

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.