Estradiol-Levonorgestrel Patch, Transdermal Weekly Side Effects by Likelihood and Severity

COMMON side effects


If experienced, these tend to have a Severe expression

  • Abnormally Long Or Heavy Periods
  • Absence Of Menstrual Periods
  • Bleeding Not Related To Menstrual Period
  • Breast Pain
  • Fluid Retention In The Legs, Feet, Arms Or Hands
  • High Blood Sugar
  • Weight Gain

If experienced, these tend to have a Less Severe expression

  • A Decrease In How Often A Woman Menstruates
  • An Ovarian Cyst
  • Decreased Appetite
  • Diarrhea
  • Dizziness
  • Enlargement Of An Ovary
  • Head Pain
  • Inflammation Of The Tissue Lining The Sinuses
  • Itching
  • Low Energy
  • Mood Changes
  • Nausea
  • Nervousness
  • Skin Redness
  • Stomach Cramps
  • Swelling Of The Abdomen
  • Throat Irritation
  • Visible Water Retention
  • Vomiting
  • Weight Gain

INFREQUENT side effects


If experienced, these tend to have a Severe expression

  • A Common Cold
  • A Skin Rash
  • Breastmilk Production Not Associated With Childbirth Or Nursing
  • Depression
  • Inflammation Of The Lining Of The Stomach And Intestines

If experienced, these tend to have a Less Severe expression

  • A Migraine Headache
  • Acne
  • Altered Interest In Having Sexual Intercourse
  • Backache
  • Breast Pain
  • Bronchitis
  • Constipation
  • Difficulty Sleeping
  • Discharge Of Fluid From The Cervix
  • Dizziness
  • Drug-Induced Hot Flashes
  • Generalized Weakness
  • Hair Loss
  • Head Pain
  • Hirsutism, A Condition Of Hair Growth On Parts Of The Body Normally Without Hair
  • Inflammation Or Infection Of The Vagina
  • Nausea
  • Neck Pain
  • Skin Irritation
  • Vomiting
  • Yellow-Brown Patches On Skin

RARE side effects


If experienced, these tend to have a Severe expression

  • A Blockage In The Gallbladder
  • A Blockage Of The Bile Duct That Resulting In High Bilirubin Levels
  • A Breast Tumor
  • A Clot In The Lung
  • A Clot In The Small Veins That Carry Blood To Or From The Retina Of The Eye
  • A Heart Attack
  • A Lump In The Breast That Is Not Identifiable
  • A Significant Type Of Allergic Reaction Called Anaphylaxis
  • A Skin Rash
  • A Stroke
  • A Type Of Allergic Reaction Called Angioedema
  • Abnormally Long Or Heavy Periods
  • Absence Of Menstrual Periods
  • Acute Inflammation Of The Pancreas
  • An Epithelial Cancer Of The Ovary
  • Angina, Or Chest Pain Due To Partial Blockage Of Blood Flow In The Heart Arteries
  • Blood Clot In A Deep Vein Of The Extremities
  • Cancer In The Lining Of The Uterus
  • Cancer Of The Ovary
  • Dementia
  • Erythema Multiforme, A Type Of Allergic Skin Reaction
  • Erythema Nodosum, A Skin Condition With Red And Painful Nodules
  • Fluid Secretion From The Breast
  • High Amount Of Triglyceride In The Blood
  • Inflammation Of The Liver Called Hepatitis
  • Involuntary Muscle Movements
  • Irregular Involuntary Spasms Of Limbs Or Facial Muscles
  • Large Purple Or Brown Skin Blotches
  • Low Amount Of Calcium In The Blood
  • Non-Cancerous Cysts Causing The Breast To Feel Lumpy
  • Obstruction Of A Blood Vessel By A Blood Clot
  • Overgrowth Of The Uterine Lining
  • Throat Swelling

If experienced, these tend to have a Less Severe expression

  • A Disorder Of The Fallopian Tube
  • A Feeling Of General Discomfort Called Malaise
  • A Yeast Infection Of The Vagina And Vulva
  • Breastmilk Production Not Associated With Childbirth Or Nursing
  • Darkening Of The Skin
  • Depression
  • Diarrhea
  • Dry Skin
  • Enlarged Breasts
  • Enlarged Superficial Veins
  • Flu-Like Symptoms
  • Hair Loss
  • Heart Throbbing Or Pounding
  • High Blood Pressure
  • Hirsutism, A Condition Of Hair Growth On Parts Of The Body Normally Without Hair
  • Hives
  • Indigestion
  • Irritability
  • Joint Pain
  • Leg Cramps
  • Low Energy
  • Mood Changes
  • Muscle Spasm
  • Nervousness
  • Numbness And Tingling
  • Pain With Menstruation
  • Pelvic Pain
  • Reduced Sensation In The Mouth
  • Sensation Of Spinning Or Whirling
  • Swelling Of The Tongue
  • Trouble Breathing
  • Uterine Cramps
  • Uterine Fibroids
  • Water Retention
  • Yellow-Brown Patches On Skin

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.