You look in the mirror and notice that the dark circles in the middle of your eyes are bigger than usual. What's going on? Those dark circles are your pupils, the openings that let light enter your eye so you can see.
Muscles in the colored part of your eye, called the iris, control your pupil size. Your pupils get bigger or smaller, depending on the amount of light around you. In low light, your pupils open up, or dilate, to let in more light. When it’s bright, they get smaller, or constrict, to let in less light.
Sometimes your pupils can dilate without any change in the light. The medical term for it is mydriasis. Medicines, injuries, and diseases can all cause this eye condition.
A few medicines can affect the muscles that control your pupils and prevent them from getting smaller when light shines in. These meds include:
- Atropine (Atropen), which treats problems with heart rhythm, stomach issues, and some types of poisoning
- Antihistamines, like diphenhydramine (Benadryl, Genahist, Naramin, Sominex, Unisom)
- Decongestants, like pseudoephedrine (Afrinol, Sudafed)
- Motion sickness and anti-nausea medicines such as dimenhydrinate (Dramamine) or a scopolamine patch
- Parkinson's medications such as amantadine (Symmetrel) and carbidopa-levodopa (Sinemet)
- Tricyclic antidepressants like amitriptyline (Elavil) and desipramine (Norpramin)
- Botulinum toxin (Botox, Myobloc)
- Anti-seizure drugs, such as phenobarbital (Luminal) and topiramate (Topamax)
Dilated pupils are one sign that someone has used illegal drugs, such as:
These drugs affect the muscle that widens the pupil, slowing how it reacts to light. So even in a bright room, the eyes stay dilated. Withdrawal from these drugs can also make the pupils stay open wide.
Brain Injury or Disease
Pressure that builds inside your brain after a head injury, stroke, or tumor can damage the muscles in your iris that normally make your pupils open and close. One or both of your pupils can become fixed in the dilated position and can’t react to light. If that happens, you should see a doctor right away.
An eye injury can damage nerves or the muscles in your iris that control your pupil size. That can also happen after eye surgery, such as cataract removal or corneal transplant.
Benign Episodic Unilateral Mydriasis
This condition means only one pupil is dilated. It's called "benign" because it's not related to any serious conditions, but it can sometimes affect young women who get migraines. The pupil usually goes back to normal size within a few hours, but it can last for several days.
When to See Your Doctor
See your doctor or ophthalmologist for an exam if your pupils are enlarged and they don't get smaller in bright light. Get emergency help if you've had a head injury and your pupils look larger -- especially if one pupil is bigger than the other.
How to Manage Dilated Pupils
If a medicine caused your pupils to dilate, they should go back to normal once the drug wears off. Try to avoid the drug in the future, if you can. If you need the medication for a health problem, ask your doctor if there’s a different drug you can try that won’t affect your eyes.
While your eyes are dilated, they will be more sensitive to light than usual. Try to avoid bright places. Wear sunglasses when you go outside. Sometimes dilated pupils can affect your vision. Ask your eye doctor if you need to avoid driving until your pupils go back to their normal size.