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    1,4 - DMAA

    Other Names:

    1,4-Dimethylamylamine, 1,4-Dimethylpentylamine, 1,4 Dimethylamylamine, 1,4 Dimethylpentylamine, 1,4 DMAA, 2-Amino-5-Methylhexane, 5-Methyl-2-Hexanamine, 5-methylhexan-2-amine.

    1,4-DMAA Overview
    1,4-DMAA Uses
    1,4-DMAA Side Effects
    1,4-DMAA Interactions
    1,4-DMAA Dosing
    1,4-DMAA Overview Information

    1,4-DMAA is a chemical with stimulant effects.

    1,4-DMAA is used for athletic performance and obesity, but there is no good scientific evidence to support these uses. Taking 1,4-DMAA might also be unsafe.

    1,4-DMAA is found in small amounts in geranium plants. However, some supplements have been found to contain much larger amounts than are found in nature. Because of this, there is a concern that manufacturers are using synthetic 1,4-DMAA that is made in a laboratory rather than obtaining it from a natural source. The US Food and Drug Administration (FDA) states that supplements containing 1,4-DMAA appear to be illegal and recommends that these products not be taken. 1,4-DMAA is also included in the World Anti-Doping Agency's prohibited substances list. Competitive athletes should avoid taking it.

    How does it work?

    1,4-DMAA is thought to have stimulant effects. Stimulants can increase energy and focus and decrease hunger. However, there is no good scientific evidence to support the use of 1,4-DMAA for these effects.

    1,4-DMAA Uses & Effectiveness What is this?

    Insufficient Evidence for:

    • Athletic performance.
    • Obesity.
    • Other conditions.
    More evidence is needed to rate 1,4-DMAA for these uses.

    1,4-DMAA Side Effects & Safety

    When taken by mouth: 1,4-DMAA is LIKELY UNSAFE when taken by mouth. Since it's thought to work like a stimulant, there is concern that it might increase the chance of serious side effects such as rapid heartbeat, increased blood pressure, and increased risk of heart attack or stroke.

    Special Precautions & Warnings:

    Pregnancy and breast-feeding: There isn't enough reliable information to know if 1,4-DMAA is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

    High blood pressure: 1,4-DMAA might have stimulant effects and can increase blood pressure. If you have high blood pressure, avoid taking 1,4-DMAA.

    Glaucoma: 1,4-DMAA might have stimulant effects and cause blood vessels to constrict. This could worsen some types of glaucoma. If you have glaucoma, avoid taking 1,4-DMAA.

    Irregular heartbeat (heart arrhythmia): 1,4-DMAA might have stimulant effects and can cause a rapid heartbeat. This could worsen heartarrhythmias.

    Surgery: 1,4-DMAA might have stimulant effects, so it might interfere with surgery by increasing heart rate and blood pressure. Stop taking 1,4-DMAA at least 2 weeks before a scheduled surgery.

    1,4-DMAA Interactions What is this?

    We currently have no information for 1,4-DMAA Interactions

    1,4-DMAA Dosing

    The appropriate dose of 1,4-DMAA depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for 1,4-DMAA. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

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    Conditions of Use and Important Information: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

    This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. © Therapeutic Research Faculty 2009.

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