Adenosine blocks electrical signals in the heart that cause irregular heart rhythms. ATP might also prevent changes in energy metabolism that cause weight loss in people with advanced cancer.
An injectable form of adenosine is a US FDA-approved prescription drug for a condition involving rapid heart rate (paroxysmal supraventricular tachycardia). It is also used as a prescription drug to help measure blockages in the arteries of the heart. People also use adenosine, AMP, and ATP as supplements for athletic performance, cold sores, and many other purposes, but there is no good evidence to support these uses.
Uses & Effectiveness
Likely Effective for
- A heart condition marked by episodes of rapid heart rate (paroxysmal supraventricular tachycardia). Adenosine is a prescription-only IV medicine approved to treat certain kinds of irregular heartbeat. This product can only be given by a healthcare provider.
- Diagnosing heart disease. Adenosine is a prescription-only IV medicine approved to diagnose coronary artery disease. This product can only be given by a healthcare provider.
Possibly Effective for
- Involuntary weight loss in people who are very ill (cachexia or wasting syndrome). Giving ATP by IV seems to improve appetite, food intake, and quality of life in people with advanced non-small-cell lung cancer and other tumors. IV products can only be given by a healthcare provider.
Possibly Ineffective for
- Heart attack. Giving adenosine by IV or injection directly into the heart vessels during procedures for a heart attack doesn't seem to reduce death or serious complications. IV products can only be given by a healthcare provider.
- Pain after surgery. Giving adenosine by IV after surgery doesn't seem to reduce pain or the use of pain medication. IV products can only be given by a healthcare provider.
- Nausea and vomiting after surgery. Giving adenosine by IV after surgery doesn't seem to reduce nausea or vomiting. IV products can only be given by a healthcare provider.
Special Precautions and Warnings
Pregnancy and breast-feeding: There isn't enough reliable information to know if adenosine is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.
Dipyridamole (Persantine) interacts with ADENOSINE
Dipyridamole can slow down how quickly the body gets rid of adenosine. This increases the risk for serious side effects from adenosine. Do not take adenosine if you are taking dipyridamole.
Do not take this combination
Carbamazepine (Tegretol) interacts with ADENOSINE
Adenosine can slow down the heartbeat. Taking carbamazepine with adenosine might cause the heart to beat too slowly.
Be cautious with this combination
Methylxanthines interacts with ADENOSINE
Methylxanthines might block the effects of adenosine. Adenosine is often used by doctors to do a test on the heart. This test is called a cardiac stress test. Stop taking methylxanthines at least 24 hours before a cardiac stress test.
Be watchful with this combination
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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.
This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2020.