MAQUI: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews

Overview

Maqui (Aristotelia chilensis) is a plant with edible purple berries. It grows in Chile and Argentina. Its berries and juice are used as food and medicine.

Maqui berries and juice contain chemicals that act as antioxidants, which are thought to protect body cells from damage.

People use maqui for dry eye, prediabetes, and many other conditions, but there is no good scientific evidence to support these uses.

Uses & Effectiveness ?

We currently have no information for MAQUI overview.

Side Effects

When taken by mouth: Maqui is possibly safe when used in doses up to 180 mg daily for up to 3 months. There isn't enough information to know what the side effects might be.

Special Precautions and Warnings

When taken by mouth: Maqui is possibly safe when used in doses up to 180 mg daily for up to 3 months. There isn't enough information to know what the side effects might be.

Pregnancy and breast-feeding: There isn't enough reliable information to know if maqui is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Interactions ?

Minor Interaction

Be watchful with this combination

Medications for diabetes (Antidiabetes drugs) interacts with MAQUI
Maqui might lower blood sugar levels. Taking maqui along with diabetes medications might cause blood sugar to drop too low. Monitor your blood sugar closely.

Dosing

There isn't enough reliable information to know what an appropriate dose of maqui might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.

View References

REFERENCES:

Escribano-Bailón MT, Alcalde-Eon C, Muñoz O, et al. Anthocyanins in berries of Maqui (Aristotelia chilensis (Mol.) Stuntz). Phytochem Anal 2006;17:8-14. View abstract.

Miranda-Rottmann S, Aspillaga AA, Pérez DD, et al. Juice and phenolic fractions of the berry Aristotelia chilensis inhibit LDL oxidation in vitro and protect human endothelial cells against oxidative stress. J Agric Food Chem 2002;50:7542-7. View abstract.

Rubilar M, Jara C, Poo Y, et al. Extracts of maqui (Aristotelia chilensis) and murta (Ugni molinae Turcz.): sources of antioxidant compounds and alpha-glucosidase/alpha-amylase inhibitors. J Agric Food Chem 2011;59:1630-7. View abstract.

Ruiz A, Hermosín-Gutiérrez I, Mardones C, et al. Polyphenols and antioxidant activity of calafate ( Berberis microphylla ) fruits and other native berries from Southern Chile. J Agric Food Chem 2010;58:6081-9. View abstract.

Suwalsky M, Vargas P, Avello M, et al. Human erythrocytes are affected in vitro by flavonoids of Aristotelia chilensis (Maqui) leaves. Int J Pharm 2008;363:85-90. View abstract.

Agulló V, González-Trujano ME, Hernandez-Leon A, Estrada-Camarena E, Pellicer F, García-Viguera C. Antinociceptive effects of maqui-berry (Aristotelia chilensis (Mol.) Stuntz). Int J Food Sci Nutr. 2021 Nov;72(7):947-55. View abstract.

Alvarado J, Schoenlau F, Leschot A, Salgad AM, Vigil Portales P. Delphinol® standardized maqui berry extract significantly lowers blood glucose and improves blood lipid profile in prediabetic individuals in three-month clinical trial. Panminerva Med. 2016;58(3 Suppl 1):1-6. View abstract.

Alvarado JL, Leschot A, Olivera-Nappa Á, et al. Delphinidin-rich maqui berry extract (Delphinol®) lowers fasting and postprandial glycemia and insulinemia in prediabetic individuals during oral glucose tolerance tests. Biomed Res Int. 2016;2016:9070537. View abstract.

Davinelli S, Bertoglio JC, Zarrelli A, Pina R, Scapagnini G. A randomized clinical trial evaluating the efficacy of an anthocyanin-maqui berry extract (Delphinol®) on oxidative stress biomarkers. J Am Coll Nutr. 2015;34 Suppl 1:28-33. View abstract.

Escribano-Bailón MT, Alcalde-Eon C, Muñoz O, et al. Anthocyanins in berries of Maqui (Aristotelia chilensis (Mol.) Stuntz). Phytochem Anal 2006;17:8-14. View abstract.

Hidalgo J, Flores C, Hidalgo MA, et al. Delphinol® standardized maqui berry extract reduces postprandial blood glucose increase in individuals with impaired glucose regulation by novel mechanism of sodium glucose cotransporter inhibition. Panminerva Med. 2014;56(2 Suppl 3):1-7. View abstract.

Hitoe S, Tanaka J, Shimoda H. MaquiBright standardized maqui berry extract significantly increases tear fluid production and ameliorates dry eye-related symptoms in a clinical pilot trial. Panminerva Med. 2014;56(3 Suppl 1):1-6.View abstract.

Rodríguez L, Trostchansky A, Wood I, et al. Antiplatelet activity and chemical analysis of leaf and fruit extracts from Aristotelia chilensis. PLoS One. 2021 Apr 28;16(4):e0250852. View abstract.

Schön C, Wacker R, Micka A, Steudle J, Lang S, Bonnländer B. Bioavailability study of maqui berry extract in healthy subjects. Nutrients. 2018;10(11). pii: E1720. View abstract.

Suwalsky M, Vargas P, Avello M, et al. Human erythrocytes are affected in vitro by flavonoids of Aristotelia chilensis (Maqui) leaves. Int J Pharm 2008;363:85-90. View abstract.

Vergara D, Ávila D, Escobar E, Carrasco-Pozo C, Sánchez A, Gotteland M. The intake of maqui (Aristotelia chilensis) berry extract normalizes H2O2 and IL-6 concentrations in exhaled breath condensate from healthy smokers - an explorative study. Nutr J. 2015;14:27. View abstract.

Viuda-Martos M, Lucas-Gonzalez R, Ballester-Costa C, Pérez-Álvarez JA, Muñoz LA, Fernández-López J. Evaluation of protective effect of different dietary fibers on polyphenolic profile stability of maqui berry (Aristotelia chilensis (Molina) Stuntz) during in vitro gastrointestinal digestion. Food Funct. 2018;9(1):573-584. View abstract.

CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2020.

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