Calea zacatechichi is a shrub used by native peoples of Mexico to increase dreams and for its hallucinogenic effects. It might also increase appetite.

It's unclear how Calea zacatechichi works. It seems to have an effect on sleep that might lengthen shallow sleep patterns, increase dream memory, and increase sleep awakenings throughout the night.

People use Calea zacatechichi for anxiety, insomnia, memory and thinking skills, diabetes, and headache, but there is no good scientific evidence to support any use.

Calea zacatechichi is legal in supplements in the U.S., except in Louisiana.

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