METHYLPENTANE

OTHER NAME(S):

1,3-Dimethylbutanamine, 1,3-dimethylbutylamine, 1,3-Dimethyl-Butylamine, 1,3-Dimethylbutylamine Citrate, 2-Amino-4-Methylpentane, 4-AMP, 4-Amino-2-Methylpentane Citrate, 4-Amino-2-Pentanamine, 4-Methyl-2-Pentanamine, 4-Methylpentan-2-Amine, AMP citrate, Dimethylbutylamine, DMBA, Methylpentane Citrate.<br/><br/>

Overview

Overview Information

Methylpentane is a chemical that is similar to the unsafe chemical 1,3-dimethylamylamine (DMAA) that has been banned by the US Food and Drug Administration. It is commonly found in supplements that claim to help people lose weight, improve athletic performance, and improve brain function.

How does it work?

Methylpentane works like a stimulant and is similar to the chemical DMAA. Like DMAA, it can cause blood vessels to contract in some parts of the body and speed up heart rate.

Uses

Uses & Effectiveness?

Insufficient Evidence for

More evidence is needed to rate the effectiveness of methylpentane for these uses.

Side Effects

Side Effects & Safety

Taking methylpentane by mouth is POSSIBLY UNSAFE. Since it is similar to DMAA and is thought to work like a stimulant, there is concern that it might increase the chance of side effects such as rapid heartbeat, increased blood pressure, shaking, and anxiety.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Not enough is known about the use of methylpentane during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Interactions

Interactions?

We currently have no information for METHYLPENTANE Interactions.

Dosing

Dosing

The appropriate dose of methylpentane depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for methylpentane. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References

REFERENCES:

  • Adverse Event Report. Jack3d. Natural MedWatch, May 28, 2011.
  • Cohen PA, Travis JC, and Venhuis BJ. A synthetic stimulant never tested in humans, 1,3-dimethylbutylamine (DMBA), is identified in multiple dietary supplements. Drug Test Analysis.,10-8-2014.
  • Farney TM, McCarthy C, Canale RE, et al. Hemodynamic and hematologic profile of health adults ingesting dietary supplements containing 1,3-dimethylamylamine and caffeine. Nutr Metab Insights 2012;5:1-12.
  • FDA challenges marketing of DMAA products for lack of safety evidence. US Food and Drug Administration, April 27, 2012. Available at: http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm302133.htm
  • Gee P, Jackson S, Easton J. Another bitter pill: a case of toxicity from DMAA party pills. N Z Med J 2010;123:124-7. View abstract.
  • Material Safety Data Sheet. 1,3-Dimethylbutylamine, 98%. https://www.fishersci.ca/viewmsds.do?catNo=AC314700050.
  • McCarthy C, Canale RE, Alleman RJ, et al. Biochemical and anthropometric effects of a weight loss dietary supplement in health men and women. Nutr Metab Insights 2012;5:13-22.
  • McCarthy C, Farney TM, Canale RE, et al. A finished dietary supplement stimulates lipolysis and metabolic rate in young men and women. Nutr Metab Insights 2012;5:23-31.
  • Removal of the dietary supplement DMAA. Army Medicine, Office of the Surgeon General, 2011. Available at: http://humanperformanceresourcecenter.org/dietary-supplements/files/dmaa-pdf. (Accessed 4 January 2012).
  • SWANSON EE, CHEN KK. Comparison of pressor action of alicyclic derivatives of aliphatic amines. J Pharmacol Exp Ther. 1948 Aug;93(4):423-9. View abstract.
  • Adverse Event Report. Jack3d. Natural MedWatch, May 28, 2011.
  • Cohen PA, Travis JC, and Venhuis BJ. A synthetic stimulant never tested in humans, 1,3-dimethylbutylamine (DMBA), is identified in multiple dietary supplements. Drug Test Analysis.,10-8-2014.
  • Farney TM, McCarthy C, Canale RE, et al. Hemodynamic and hematologic profile of health adults ingesting dietary supplements containing 1,3-dimethylamylamine and caffeine. Nutr Metab Insights 2012;5:1-12.
  • FDA challenges marketing of DMAA products for lack of safety evidence. US Food and Drug Administration, April 27, 2012. Available at: http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm302133.htm
  • Gee P, Jackson S, Easton J. Another bitter pill: a case of toxicity from DMAA party pills. N Z Med J 2010;123:124-7. View abstract.
  • Liu Y, Santillo MF. Cytochrome P450 2D6 and 3A4 enzyme inhibition by amine stimulants in dietary supplements. Drug Test Anal. 2016;8(3-4):307-10. View abstract.
  • Material Safety Data Sheet. 1,3-Dimethylbutylamine, 98%. https://www.fishersci.ca/viewmsds.do?catNo=AC314700050.
  • McCarthy C, Canale RE, Alleman RJ, et al. Biochemical and anthropometric effects of a weight loss dietary supplement in health men and women. Nutr Metab Insights 2012;5:13-22.
  • McCarthy C, Farney TM, Canale RE, et al. A finished dietary supplement stimulates lipolysis and metabolic rate in young men and women. Nutr Metab Insights 2012;5:23-31.
  • Removal of the dietary supplement DMAA. Army Medicine, Office of the Surgeon General, 2011. Available at: http://humanperformanceresourcecenter.org/dietary-supplements/files/dmaa-pdf. (Accessed 4 January 2012).
  • SWANSON EE, CHEN KK. Comparison of pressor action of alicyclic derivatives of aliphatic amines. J Pharmacol Exp Ther. 1948 Aug;93(4):423-9. View abstract.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2018.