Overview
Many dietary supplements that list Acacia rigidula as an ingredient have been shown to contain large amounts of the chemical phenethylamine. While phenethylamine is found in Acacia rigidula leaves naturally, the amounts found in these supplements is often greater than would be expected from the plant parts alone.
In addition to phenethylamine, many supplements listing Acacia rigidula as an ingredient have been found to contain another unlisted ingredient called beta-methylphenethylamine (BMPEA). This ingredient is a stimulant similar to amphetamine. But unlike phenethylamine, it is not found naturally in Acacia rigidula or any other known plants. In April 2015, the U.S. Food and Drug Administration (FDA) stated that BMPEA does not meet the definition of a dietary ingredient. Therefore, any products containing BMPEA are considered misbranded.
How does it work ?
Uses & Effectiveness
Insufficient Evidence for
- Weight loss.
- Athletic performance.
- Other conditions.
Side Effects
Special Precautions and Warnings
Pregnancy and breast-feeding: There is not enough reliable information about the safety of taking Acacia rigidula if you are pregnant or breast feeding. Stay on the safe side and avoid use.
High blood pressure: Some chemicals in Acacia rigidula have stimulant effects. Many products that list Acacia rigidula as an ingredient have also been found to contain a chemical called beta-methylphenethylamine (BMPEA). BMPEA and other stimulants can increase blood pressure and heart rate. In theory, taking Acacia rigidula supplements might make high blood pressure worse.
Surgery: Some chemicals in Acacia rigidula have stimulant effects. Many products that list Acacia rigidula as an ingredient have also been found to contain a chemical called beta-methylphenethylamine (BMPEA). BMPEA and other stimulants can increase blood pressure and heart rate. In theory, taking Acacia rigidula supplements might interfere with surgery by increasing blood pressure and heart rate. Stop taking Acacia rigidula supplements at least 2 weeks before surgery.
Interactions
Stimulant Drugs interacts with ACACIA RIGIDULA
Stimulant drugs speed up the nervous system. By speeding up the nervous system, stimulant medications can make you feel jittery and speed up your heart rate. Some chemicals in Acacia rigidula also have stimulant effects. Many products that list Acacia rigidula as an ingredient have also been found to contain an amphetamine-like chemical called beta-methylphenethylamine (BMPEA). In theory, taking Acacia rigidula along with stimulant drugs might cause serious problems, such as causing heart rate and blood pressure to become too high.
Some stimulant drugs include amphetamine, caffeine, diethylpropion (Tenuate), methylphenidate, phentermine (Ionamin), pseudoephedrine (Sudafed, others), and many others.Medications changed by the liver (Cytochrome P450 2D6 (CYP2D6) substrates) interacts with ACACIA RIGIDULA
Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with ACACIA RIGIDULA
Moderate Interaction
Be cautious with this combination
Dosing
CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.
This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2020.