Overview

Antineoplastons are peptides found in the urine and blood of healthy people. The chemical structures of antineoplastons were determined in the 1980s. Today, most antineoplastons are prepared in a laboratory.

Antineoplastons are used for various cancers, high cholesterol, brain swelling due to infection (encephalitis), HIV/AIDS, Parkinson disease, and other conditions, but there is no good scientific evidence to support these uses.

How does it work ?

Antineoplastons might stimulate the immune system. These peptides might also kill certain cancer cells or prevent them from growing.

Antineoplastons might stimulate the immune system. These peptides might also kill certain cancer cells or prevent them from growing.

Uses & Effectiveness ?

Insufficient Evidence for

  • Brain tumor. Early research shows that using antineoplastons along with standard medications after radiation and surgery might help reduce the size of brain tumors in some people. Other early research shows that injecting antineoplastons intravenously (by IV) might help reduce the size of a specific type of brain tumor, called a glioma, in some adults and children. But other research shows that antineoplastons don't reduce tumor size in people with gliomas. All of the research to date is low-quality.
  • Colon cancer. Early research shows that injecting antineoplastons intravenously (by IV) and then taking them by mouth might help people with colon cancer to live longer after having a part of their liver removed.
  • A rare tumor that affects the central nervous system (primitive neuroectodermal tumor or PNET). Injecting antineoplastons intravenously (by IV) might help reduce the size of PNETs or keep PNETs from becoming larger in some children with PNET. However, the research to date is low-quality.
  • Prostate cancer. Injecting antineoplastons along with the drug diethylstilbestrol might increase the chance of remission in people with prostate cancer. However, the research to date is low-quality.
  • Breast cancer.
  • Liver cancer.
  • Lung cancer.
  • High cholesterol.
  • Brain swelling due to infection (encephalitis).
  • HIV/AIDS.
  • Parkinson disease.
  • Sickle cell anemia.
  • An inherited blood disorder called thalassemia.
  • Other conditions.
More evidence is needed to rate the effectiveness of antineoplastons for these uses.

Side Effects

When taken by mouth: Antineoplastons A10 and AS2-1 are POSSIBLY SAFE in appropriate amounts when used short-term under the supervision of a healthcare professional. Antineoplastons A10 and AS2-1 are POSSIBLY UNSAFE in higher doses or for longer periods of time. Giving antineoplastons in higher doses or for longer periods of time seems to increase the number of side effects. There isn't enough reliable information to know if other types of antineoplastons are safe.

When given by IV: Antineoplastons A10 and AS2-1 are POSSIBLY SAFE in appropriate amounts when given short-term by a healthcare professional. Antineoplastons A10 and AS2-1 are POSSIBLY UNSAFE when given in higher doses or for longer periods of time. Giving antineoplastons in higher doses or for longer periods of time seems to increase the number of side effects. There isn't enough reliable information to know if other types of antineoplastons are safe.

Side effects of antineoplastons include irregular heartbeat, increased blood pressure, skin rash, nausea, vomiting, stomach pain, gas, liver problems, joint swelling, muscle and joint pain, weakness, tiredness, headache, ringing in the ears, dizziness, and fever.

Special Precautions and Warnings

When taken by mouth: Antineoplastons A10 and AS2-1 are POSSIBLY SAFE in appropriate amounts when used short-term under the supervision of a healthcare professional. Antineoplastons A10 and AS2-1 are POSSIBLY UNSAFE in higher doses or for longer periods of time. Giving antineoplastons in higher doses or for longer periods of time seems to increase the number of side effects. There isn't enough reliable information to know if other types of antineoplastons are safe.

When given by IV: Antineoplastons A10 and AS2-1 are POSSIBLY SAFE in appropriate amounts when given short-term by a healthcare professional. Antineoplastons A10 and AS2-1 are POSSIBLY UNSAFE when given in higher doses or for longer periods of time. Giving antineoplastons in higher doses or for longer periods of time seems to increase the number of side effects. There isn't enough reliable information to know if other types of antineoplastons are safe.

Side effects of antineoplastons include irregular heartbeat, increased blood pressure, skin rash, nausea, vomiting, stomach pain, gas, liver problems, joint swelling, muscle and joint pain, weakness, tiredness, headache, ringing in the ears, dizziness, and fever.
Pregnancy and breast-feeding: There isn't enough reliable information to know if it is safe to use antineoplastons when pregnant or breast-feeding. Stay on the safe side and avoid use.

Interactions ?

We currently have no information for ANTINEOPLASTONS overview.

Dosing

The appropriate dose of antineoplastons depends on several factors such as the user's age, health, and several other conditions. At this time, there is not enough scientific information to determine an appropriate range of doses for antineoplastons. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2020.