1-ANDROSTERONE

OTHER NAME(S):

1-Androsten-3beta-ol-17-one, 1-Androstène-3bêta-ol-17-one, 1-Androstene-3beta-ol-17-one, 1-Androstène-3bêta-ol-17-one, 1-Androstene-3beta-ol,17-one, 1-Androstène-3bêta-ol,17-one, 1-DHEA, 3-hydroxy-5alpha-androstan-1-en-17-one, 3-hydroxy-5alpha-androst-1-en-17-one, 3-hydroxyandrost-1-en-17-one, 3beta-hydroxy-5alpha-androst-1-en-17-one, 3beta-hydroxy-androst-1-ene-17-one.

Overview

Overview Information

1-Androsterone is a type of chemical known as a "prohormone." These chemicals are changed by the body to other "muscle-building" hormones such as testosterone. Very little is known about the safety of 1-androsterone. There is concern it might cause serious side effects similar to those caused by other "muscle-building" hormones.

1-Androsterone is included as an ingredient in a variety of supplements marketed to athletes and bodybuilders.

How does it work?

After 1-androsterone is taken, the body changes it into other chemicals called hormones. Some of these hormones are very similar to testosterone. Testosterone can help build muscle, but can also cause dangerous side effects.
Uses

Uses & Effectiveness?

Insufficient Evidence for

  • Athletic performance. Early research shows that taking 1-androsterone 330 mg daily might help increase strength in people who lift weights. It might also help lower body fat.
  • Other conditions.
More evidence is needed to rate 1-androsterone for this use.

Side Effects

Side Effects & Safety

1-androsterone is POSSIBLY UNSAFE when taken by mouth. Early research shows that taking 1-androsterone might cause liver and kidney damage and also increase cholesterol.

Special Precautions & Warnings:

Pregnancy and breast-feeding: 1-androsterone is POSSIBLY UNSAFE when used orally during pregnancy or breast-feeding. 1-Androsterone is changed by the body to hormones which are similar to testosterone. These hormones might cause harm to pregnant women, unborn babies, or nursing infants.

High cholesterol: 1-Androsterone might worsen cholesterol. This could increase the risk for heart attacks, stroke, or death in patients with high cholesterol.

Kidney disease: 1-Androsterone might damage the kidney and worsen kidney disease in some people.

Liver problems: 1-Androsterone might damage the liver and worsen liver problems in some people.

Interactions

Interactions?

We currently have no information for 1-ANDROSTERONE Interactions.

Dosing

Dosing

The appropriate dose of 1-androsterone depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for 1-androsterone. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References

REFERENCES:

  • Bourke CA, Carrigan MJ, Dixon RJ. Experimental evidence that tryptamine alkaloids do not cause Phalaris aquatic sudden death syndrome in sheep. Aust Vet J 1988;65(7):218-20. View abstract,
  • Granados J, Gillum TL, Christmas KM, et al. Prohormone supplement 3b-hydroxy-5a-androst-1-en-17-one enhances resistance training gains but impairs user health. J Appl Physiol (1985). 2014;116(5):560-9. View abstract.
  • Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100. View abstract.
  • Parr MK, Opfermann G, Geyer H, et al. Seized designer supplement named "1-Androsterone": identification as 3ß-hydroxy-5a-androst-1-en-17-one and its urinary elimination. Steroids 2011;76(6):540-7. View abstract.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2018.