L-ornithine-L-aspartate is most commonly used for reduced brain function in people with advanced liver disease (hepatic encephalopathy). It is also used for athletic performance, cirrhosis, and other conditions, but there is no good scientific evidence to support these uses.
How does it work ?
Uses & Effectiveness ?
Possibly Effective for
- Reduced brain function in people with advanced liver disease (hepatic encephalopathy). Most research shows that L-ornithine-L-aspartate may reduce symptoms of hepatic encephalopathy in people with a liver disease called cirrhosis. But most of this research is low-quality. And not all people who get hepatic encephalopathy have cirrhosis. L-ornithine-L-aspartate might not help reduce symptoms in people with other causes of hepatic encephalopathy.
Insufficient Evidence for
- Liver scarring (cirrhosis). Research shows that giving L-ornithine-L-aspartate by mouth or with a needle might reduce the risk of death in people with cirrhosis. But not all research agrees. More research is needed to understand if L-ornithine-L-aspartate can help people with cirrhosis.
- To improve mental performance during exercise.
- Involuntary weight loss in people who are very ill (cachexia or wasting syndrome).
- Wound healing.
- Other conditions.
When given by IV: L-ornithine-L-aspartate is POSSIBLY SAFE when given by IV. Nausea, vomiting, cough, muscle cramping, and diarrhea have happened in some people getting injections of L-ornithine-L-aspartate. But these side effects are rare.
Special Precautions and Warnings
We currently have no information for L-ORNITHINE-L-ASPARTATE overview.
- For reduced brain function in people with advanced liver disease (hepatic encephalopathy): 9-18 grams daily for up to 3 months has been used.
- For reduced brain function in people with advanced liver disease (hepatic encephalopathy): 5-40 grams daily for up to 7 days has been used.
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