Zeaxanthin is a type of organic pigment called a carotenoid. It's related to vitamin A and found in the human eye (macula and retina) along with lutein.

Zeaxanthin is thought to function as a light filter, protecting the eye tissues from sunlight damage. Foods rich in zeaxanthin include eggs, oranges, grapes, corn, goji berries, mango, orange pepper, and some other vegetables and fruits.

People use zeaxanthin for age-related vision loss. It's also used for eye strain, mental decline, heart disease, breast cancer, cataracts, and many other conditions, but there's no good scientific evidence to support these uses.

Uses & Effectiveness ?

Possibly Effective for

  • An eye disease that leads to vision loss in older adults (age-related macular degeneration or AMD). Taking zeaxanthin by mouth as part of a combination product that also contains lutein seems to help improve vision in people with AMD. But it's not clear if taking zeaxanthin without lutein helps.
There is interest in using zeaxanthin for a number of other purposes, but there isn't enough reliable information to say whether it might be helpful.

Side Effects

When taken by mouth: Zeaxanthin is likely safe when used in doses up to 2 mg daily. It is possibly safe when taken in larger doses. Doses up to 10 mg daily seem to be safe when used for up to 1 year.

Special Precautions and Warnings

Pregnancy and breast-feeding: Zeaxanthin is commonly consumed in foods. There isn't enough reliable information to know if zeaxanthin is safe to use as medicine while pregnant or breast-feeding. Stay on the safe side and stick to food amounts.

Children: Zeaxanthin is possibly safe when taken by mouth in appropriate amounts. A specific product (LUTEINofta, SOOFT Italia SpA) containing zeaxanthin 0.0006 mg daily has been safely used in infants for 36 weeks.

Interactions ?

    Moderate Interaction

    Be cautious with this combination

  • Medications for diabetes (Antidiabetes drugs) interacts with ZEAXANTHIN

    Zeaxanthin might lower blood sugar levels. Taking zeaxanthin along with diabetes medications might cause blood sugar to drop too low. Monitor your blood sugar closely.


Zeaxanthin is found in many foods, with orange pepper being the richest source. Other sources include egg yolks, corn, red grapes, oranges, honeydew melon, and mango.

Zeaxanthin is also taken in supplements, typically along with lutein. It's most often been used by adults in doses of 2 mg by mouth daily, for up to 4.8 years. Zeaxanthin is absorbed best when it's taken with a high-fat meal. Speak with a healthcare provider to find out what type of product or dose might be best for a specific condition.
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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. © Therapeutic Research Faculty 2018.