BETA-CRYPTOXANTHIN: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews

Overview

Beta-cryptoxanthin is a type of organic pigment called a carotenoid. It's related to vitamin A and found in high levels in the blood.

Beta-cryptoxanthin is similar to other carotenoids, including beta-carotene, lutein, and zeaxanthin. Foods rich in beta-cryptoxanthin include squash, peppers, tangerines, oranges, peaches, and papaya.

People use beta-cryptoxanthin for cancer, diabetes, obesity, liver disease, and many other conditions, but there is no good scientific evidence to support these uses.

Don't confuse beta-cryptoxanthin with other carotenoids, including beta-carotene, lutein, and zeaxanthin. These are not the same.

Uses & Effectiveness ?

We currently have no information for BETA-CRYPTOXANTHIN overview.

Side Effects

When taken by mouth: Beta-cryptoxanthin is commonly consumed in foods. It is possibly safe when used as a supplement in doses of 6 mg daily.

Special Precautions and Warnings

When taken by mouth: Beta-cryptoxanthin is commonly consumed in foods. It is possibly safe when used as a supplement in doses of 6 mg daily.

Pregnancy and breast-feeding: Beta-cryptoxanthin is commonly consumed in foods. There isn't enough reliable information to know if beta-cryptoxanthin is safe to use in larger amounts as medicine while pregnant or breast-feeding. Stay on the safe side and stick to food amounts.

Interactions ?

We currently have no information for BETA-CRYPTOXANTHIN overview.

Dosing

Beta-cryptoxanthin is naturally found in foods such as squash, peppers, tangerines, oranges, peaches, and papaya. But as medicine, there isn't enough reliable information to know what an appropriate dose of beta-cryptoxanthin might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.

View References

REFERENCES:

Aschoff JK, Rolke CL, Breusing N, et al. Bioavailability of beta-cryptoxanthin is greater from pasteurized orange juice than from fresh oranges - a randomized cross-over study. Mol Nutr Food Res 2015;59(10):1896-904. View abstract.

Aune D, Keum N, Giovannucci E, et al. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies. Am J Clin Nutr 2018;108(5):1069-1091. View abstract.

Breithaupt DE, Weller P, Wolters M, Hahn A. Plasma response to a single dose of dietary beta-cryptoxanthin esters from papaya (Carica papaya L.) or non-esterified beta-cryptoxanthin in adult human subjects: a comparative study. Br J Nutr 2003;90(4):795-801. View abstract.

Burri BJ, La Frano MR, Zhu C. Absorption, metabolism, and functions of beta-cryptoxanthin. Nutr Rev 2016;74(2):69-82. View abstract.

Curhan SG, Stankovic KM, Eavey RD, Wang M, Stampfer MJ, Curhan GC. Carotenoids, vitamin A, vitamin C, vitamin E, and folate and risk of self-reported hearing loss in women. Am J Clin Nutr 2015;102(5):1167-75. View abstract.

Ge XX, Xing MY, Yu LF, et al. Carotenoid intake and esophageal cancer risk: a meta-analysis. Asian Pac J Cancer Prev. 2013;14(3):1911-8. View abstract.

Granado-Lorencio F, Lagarda MJ, Garcia-López FJ, et al. Effect of beta-cryptoxanthin plus phytosterols on cardiovascular risk and bone turnover markers in post-menopausal women: a randomized crossover trial. Nutr Metab Cardiovasc Dis 2014;24(10):1090-6. View abstract.

Haidari F, Hojhabrimanesh A, Helli B, Seyedian SS, Ahmadi-Angali K, Abiri B. A hypocaloric high-protein diet supplemented with beta-cryptoxanthin improves non-alcoholic fatty liver disease: a randomized controlled trial. BMC Gastroenterol 2020;20(1):349. View abstract.

Hirose A, Terauchi M, Hirano M, et al. Higher intake of cryptoxanthin is related to low body mass index and body fat in Japanese middle-aged women. Maturitas 2017;96:89-94. View abstract.

Iwata A, Fujiwara S, Matsubara S, Miyazaki K. Intake of beta-cryptoxanthin with fat-containing food increases ß-cryptoxanthin serum level and palmar yellowness in healthy adults. Nutr Res 2019;71:65-71. View abstract.

Kang T, Liu Y, Chen X, et al. Dietary carotenoid intake and risk of developing preeclampsia: a hospital-based case-control study. BMC Pregnancy Childbirth 2022;22(1):427. View abstract.

Kim SJ, Anh NH, Diem NC, et al. Effects of beta-cryptoxanthin on improvement in osteoporosis risk: A systematic review and meta-analysis of observational studies. Foods 2021;10(2):296. View abstract.

Kobori M, Ni Y, Takahashi Y, et al. Beta-cryptoxanthin alleviates diet-induced nonalcoholic steatohepatitis by suppressing inflammatory gene expression in mice. PLoS One 2014;9(5):e98294. View abstract.

Leoncini E, Nedovic D, Panic N, Pastorino R, Edefonti V, Boccia S. Carotenoid intake from natural sources and head and neck cancer: A systematic review and meta-analysis of epidemiological studies. Cancer Epidemiol Biomarkers Prev 2015;24(7):1003-11. View abstract.

Qiu Z, Chen X, Geng T, et al. Associations of serum carotenoids with risk of cardiovascular mortality among individuals with type 2 diabetes: Results from NHANES. Diabetes Care 2022;45(6):1453-1461. View abstract.

Sengngam K, Hoc TH, Hang DV, Tran Ngoan L. Trans-Lycopene and ß-Cryptoxanthin Intake and Stomach Cancer in Vietnamese Men: A Pilot Case-Control Study. Asian Pac J Cancer Prev 2022;23(3):861-865. View abstract.

Uchiyama S, Yamaguchi M. Oral administration of beta-cryptoxanthin prevents bone loss in streptozotocin-diabetic rats in vivo. Biol Pharm Bull 2005;28(9):1766-9. View abstract.

Umigai N, Murakami K, Shimizu R, Takeda R, Azuma T. Safety evaluation and plasma carotenoid accumulation in healthy adult subjects after 12 weeks of paprika oleoresin supplementation. J Oleo Sci 2018;67(2):225-234. View abstract.

Wang L, Li B, Pan MX, Mo XF, Chen YM, Zhang CX. Specific carotenoid intake is inversely associated with the risk of breast cancer among Chinese women. Br J Nutr 2014;111(9):1686-95. View abstract.

Wu S, Liu Y, Michalek JE, et al. Carotenoid intake and circulating carotenoids are inversely associated with the risk of bladder cancer: A dose-response meta-analysis. Adv Nutr 2020;11(3):630-643. View abstract.

Yuan JM, Stram DO, Arakawa K, Lee HP, Yu MC. Dietary cryptoxanthin and reduced risk of lung cancer: the Singapore Chinese Health Study. Cancer Epidemiol Biomarkers Prev 2003;12(9):890-8. View abstract.

Zhang W, Li W, Du J. Association between dietary carotenoid intakes and the risk of asthma in adults: a cross-sectional study of NHANES, 2007-2012. BMJ Open 2022;12(6):e052320. View abstract.

CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2020.

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BETA-CRYPTOXANTHIN - Uses, Side Effects, and More