Carvacrol, Dostenkraut, European Oregano, Huile d’Origan, Marjolaine Bâtarde, Marjolaine Sauvage, Marjolaine Vivace, Mediterranean Oregano, Mountain Mint, Oil of Oregano, Oregano Oil, Organy, Origan, Origan Européen, Origani Vulgaris Herba, Origano, Origanum, Origanum vulgare, Phytoprogestin, Thé Sauvage, Thym des Bergers, Wild Marjoram, Winter Marjoram, Wintersweet.<br/><br/>
Overview InformationOregano is a plant. The leaf is used to make medicine.
Oregano is used for respiratory tract disorders such as coughs, asthma, croup, and bronchitis. It is also used for gastrointestinal (GI) disorders such as heartburn and bloating. Other uses include treating menstrual cramps, rheumatoid arthritis, urinary tract disorders including urinary tract infections (UTIs), headaches, and heart conditions.
The oil of oregano is taken by mouth for intestinal parasites, allergies, sinus pain, arthritis, cold and flu, swine flu, earaches, and fatigue. It is applied to the skin for skin conditions including acne, athlete's foot, oily skin, dandruff, canker sores, warts, ringworm, rosacea, and psoriasis; as well as for insect and spider bites, gum disease, toothaches, muscle pain, and varicose veins. Oregano oil is also used topically as an insect repellent.
In foods and beverages, oregano is used as a culinary spice and a food preservative.
How does it work?Oregano contains chemicals that might help reduce cough and spasms. Oregano also might help digestion by increasing bile flow and fighting against some bacteria, viruses, fungi, intestinal worms, and other parasites.
Uses & Effectiveness
Possibly Effective for
- High cholesterol. Clinical research shows that taking oregano after each meal for 3 months can reduce low-density lipoprotein (LDL or “bad”) cholesterol and increase high-density lipoprotein (HDL or “good”) cholesterol in people with high cholesterol. However, total cholesterol and triglyceride levels are not affected.
- Parasites in the intestines. Taking oil of oregano for 6 weeks can kill the parasites Blastocystis hominis, Entamoeba hartmanni, and Endolimax nana.
Insufficient Evidence for
- Bleeding disorders (hemophilia). Early research suggests that oregano might not prevent bleeding after dental procedures in people with hemophilia.
- Wound healing. Early research suggests that applying an oregano extract to the skin twice daily for up to 14 days can improve skin color, stiffness, and thickness, but does not improve itching, pain, or scars, in people who have had portions of skin removed surgically.
- Repelling insects.
- Indigestion and bloating.
- Painful menstrual periods.
- Heart conditions.
- Other conditions.
Side Effects & SafetyOregano leaf is LIKELY SAFE when taken in the amounts found in food and POSSIBLY SAFE when taken by mouth or applied to the skin in medicinal amounts. Mild side effects include stomach upset. Oregano might also cause an allergic reaction in people who have an allergy to plants in the Lamiaceae family.
Not enough is known about the safety of using oregano oil in medicinal amounts.
Special Precautions & Warnings:Pregnancy and breast-feeding: Oregano is POSSIBLY UNSAFE when taken by mouth in medicinal amounts during pregnancy. There is concern that oregano in amounts larger than food amounts might cause miscarriage. Not enough is known about the safety of oregano when used in medicinal amounts while nursing.
Bleeding disorders: Oregano might increase the risk of bleeding in people with bleeding disorders.
Allergies: Oregano can cause reactions in people allergic to Lamiaceae family plants, including basil, hyssop, lavender, marjoram, mint, and sage.
Diabetes: Oregano might lower blood sugar levels. People with diabetes should use oregano cautiously.
Surgery: Oregano might increase the risk of bleeding. People who use oregano should stop 2 weeks before surgery.
Be cautious with this combination
Lithium interacts with OREGANO
Oregano might have an effect like a water pill or "diuretic." Taking oregano might decrease how well the body gets rid of lithium. This could increase how much lithium is in the body and result in serious side effects. Talk with your healthcare provider before using this product if you are taking lithium. Your lithium dose might need to be changed.
The following doses have been studied in scientific research:
- For intestinal parasites: 200 mg of oil of oregano three times daily for 6 weeks.
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- Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. View abstract.
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- Dahiya P, Purkayastha S. Phytochemical screening and antimicrobial activity of some medicinal plants against multi-drug resistant bacteria from clinical isolates. Indian J Pharm Sci 2012;74(5):443-50. View abstract.
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- Force M, Sparks WS, Ronzio RA. Inhibition of enteric parasites by emulsified oil of oregano in vivo. Phytother Res 2000:14:213-4. View abstract.
- Fournomiti M, Kimbaris A, Mantzourani I, et al. Antimicrobial activity of essential oils of cultivated oregano (Origanum vulgare), sage (Salvia officinalis), and thyme (Thymus vulgaris) against clinical isolates of Escherichia coli, Klebsiella oxytoca, and Klebsiella pneumoniae. Microb Ecol Health Dis 2015;26:23289. View abstract.
- Hammer KA, Carson CF, Riley TV. Antimicrobial activity of essential oils and other plant extracts. J Appl Microbiol 1999;86:985-90. View abstract.
- Kivanc M, Akgul A, Dogan A. Inhibitory and stimulatory effects of cumin, oregano and their essential oils on growth and acid production of Lactobacillus plantarum and Leuconostoc mesenteroides. Int J Food Microbiol 1991;13:81-5. View abstract.
- Lukas B, Schmiderer C, Novak J. Essential oil diversity of European Origanum vulgare L. (Lamiaceae). Phytochemistry 2015;119:32-40. View abstract.
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- Teixeira B, Marques A, Ramos C, et al. Chemical composition and bioactivity of different oregano (Origanum vulgare) extracts and essential oil. J Sci Food Agric 2013;93:2707-14. View abstract.
- Ultee A, Gorris LG, Smid EJ. Bactericidal activity of carvacrol towards the food-borne pathogen Bacillus cereus. J Appl Microbiol 1998;85:211-8. View abstract.
- Ultee A, Kets EP, Smid EJ. Mechanisms of action of carvacrol on the food-borne pathogen Bacillus cereus. Appl Environ Microbiol 1999;65:4606-10. View abstract.
- Vimalanathan S, Hudson J. Anti-influenza virus activities of commercial oregano oils and their carriers. J App Pharma Sci 2012;2:214.
- Zava DT, Dollbaum CM, Blen M. Estrogen and progestin bioactivity of foods, herbs, and spices. Proc Soc Exp Biol Med 1998;217:369-78. View abstract.
- Baser, K. H. Biological and pharmacological activities of carvacrol and carvacrol bearing essential oils. Curr.Pharm.Des 2008;14(29):3106-3119. View abstract.
- Burt, S. A. and Reinders, R. D. Antibacterial activity of selected plant essential oils against Escherichia coli O157:H7. Lett.Appl.Microbiol. 2003;36(3):162-167. View abstract.
- De Martino, L., De, Feo, V, Formisano, C., Mignola, E., and Senatore, F. Chemical composition and antimicrobial activity of the essential oils from three chemotypes of Origanum vulgare L. ssp. hirtum (Link) Ietswaart growing wild in Campania (Southern Italy). Molecules. 2009;14(8):2735-2746. View abstract.
- Elgayyar, M., Draughon, F. A., Golden, D. A., and Mount, J. R. Antimicrobial activity of essential oils from plants against selected pathogenic and saprophytic microorganisms. J Food Prot. 2001;64(7):1019-1024. View abstract.
- Friedman, M., Henika, P. R., Levin, C. E., and Mandrell, R. E. Antibacterial activities of plant essential oils and their components against Escherichia coli O157:H7 and Salmonella enterica in apple juice. J Agric.Food Chem. 9-22-2004;52(19):6042-6048. View abstract.
- Futrell, J. M. and Rietschel, R. L. Spice allergy evaluated by results of patch tests. Cutis 1993;52(5):288-290. View abstract.
- Goun, E., Cunningham, G., Solodnikov, S., Krasnykch, O., and Miles, H. Antithrombin activity of some constituents from Origanum vulgare. Fitoterapia 2002;73(7-8):692-694. View abstract.
- Hawas, U. W., El Desoky, S. K., Kawashty, S. A., and Sharaf, M. Two new flavonoids from Origanum vulgare. Nat.Prod.Res 2008;22(17):1540-1543. View abstract.
- Inouye, S., Nishiyama, Y., Uchida, K., Hasumi, Y., Yamaguchi, H., and Abe, S. The vapor activity of oregano, perilla, tea tree, lavender, clove, and geranium oils against a Trichophyton mentagrophytes in a closed box. J Infect.Chemother. 2006;12(6):349-354. View abstract.
- Irkin, R. and Korukluoglu, M. Growth inhibition of pathogenic bacteria and some yeasts by selected essential oils and survival of L. monocytogenes and C. albicans in apple-carrot juice. Foodborne.Pathog.Dis. 2009;6(3):387-394. View abstract.
- Klement, A. A., Fedorova, Z. D., Volkova, S. D., Egorova, L. V., and Shul'kina, N. M. [Use of a herbal infusion of Origanum in hemophilia patients during tooth extraction]. Probl.Gematol.Pereliv.Krovi. 1978;(7):25-28. View abstract.
- Koukoulitsa, C., Karioti, A., Bergonzi, M. C., Pescitelli, G., Di Bari, L., and Skaltsa, H. Polar constituents from the aerial parts of Origanum vulgare L. Ssp. hirtum growing wild in Greece. J Agric.Food Chem. 7-26-2006;54(15):5388-5392. View abstract.
- Lambert, R. J., Skandamis, P. N., Coote, P. J., and Nychas, G. J. A study of the minimum inhibitory concentration and mode of action of oregano essential oil, thymol and carvacrol. J Appl.Microbiol. 2001;91(3):453-462. View abstract.
- Lemhadri, A., Zeggwagh, N. A., Maghrani, M., Jouad, H., and Eddouks, M. Anti-hyperglycaemic activity of the aqueous extract of Origanum vulgare growing wild in Tafilalet region. J Ethnopharmacol. 2004;92(2-3):251-256. View abstract.
- Manohar, V., Ingram, C., Gray, J., Talpur, N. A., Echard, B. W., Bagchi, D., and Preuss, H. G. Antifungal activities of origanum oil against Candida albicans. Mol.Cell Biochem. 2001;228(1-2):111-117. View abstract.
- McCue, P., Vattem, D., and Shetty, K. Inhibitory effect of clonal oregano extracts against porcine pancreatic amylase in vitro. Asia Pac.J Clin.Nutr. 2004;13(4):401-408. View abstract.
- Nostro, A., Blanco, A. R., Cannatelli, M. A., Enea, V., Flamini, G., Morelli, I., Sudano, Roccaro A., and Alonzo, V. Susceptibility of methicillin-resistant staphylococci to oregano essential oil, carvacrol and thymol. FEMS Microbiol.Lett. 1-30-2004;230(2):191-195. View abstract.
- Nurmi, A., Mursu, J., Nurmi, T., Nyyssonen, K., Alfthan, G., Hiltunen, R., Kaikkonen, J., Salonen, J. T., and Voutilainen, S. Consumption of juice fortified with oregano extract markedly increases excretion of phenolic acids but lacks short- and long-term effects on lipid peroxidation in healthy nonsmoking men. J Agric.Food Chem. 8-9-2006;54(16):5790-5796. View abstract.
- Ozdemir, B., Ekbul, A., Topal, N. B., Sarandol, E., Sag, S., Baser, K. H., Cordan, J., Gullulu, S., Tuncel, E., Baran, I., and Aydinlar, A. Effects of Origanum onites on endothelial function and serum biochemical markers in hyperlipidaemic patients. J Int Med Res 2008;36(6):1326-1334. View abstract.
- Preuss, H. G., Echard, B., Dadgar, A., Talpur, N., Manohar, V., Enig, M., Bagchi, D., and Ingram, C. Effects of Essential Oils and Monolaurin on Staphylococcus aureus: In Vitro and In Vivo Studies. Toxicol.Mech.Methods 2005;15(4):279-285. View abstract.
- Ragi, J., Pappert, A., Rao, B., Havkin-Frenkel, D., and Milgraum, S. Oregano extract ointment for wound healing: a randomized, double-blind, petrolatum-controlled study evaluating efficacy. J.Drugs Dermatol. 2011;10(10):1168-1172. View abstract.
- Rodriguez-Meizoso, I., Marin, F. R., Herrero, M., Senorans, F. J., Reglero, G., Cifuentes, A., and Ibanez, E. Subcritical water extraction of nutraceuticals with antioxidant activity from oregano. Chemical and functional characterization. J Pharm.Biomed.Anal. 8-28-2006;41(5):1560-1565. View abstract.
- Shan, B., Cai, Y. Z., Sun, M., and Corke, H. Antioxidant capacity of 26 spice extracts and characterization of their phenolic constituents. J Agric.Food Chem. 10-5-2005;53(20):7749-7759. View abstract.
- Tampieri, M. P., Galuppi, R., Macchioni, F., Carelle, M. S., Falcioni, L., Cioni, P. L., and Morelli, I. The inhibition of Candida albicans by selected essential oils and their major components. Mycopathologia 2005;159(3):339-345. View abstract.
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