Podophyllum is poisonous when taken by mouth. Despite this, some people take it orally for yellowed skin (jaundice), liver ailments, fever, syphilis, hearing loss, and cancer. Podophyllum is also used to empty the bowels, kill parasitic worms in the intestine, and counteract snakebites. Some women take it to cause an abortion.
Podophyllum has been used as a laxative. But it has been removed from the market due to safety concerns.
Podophyllum is applied directly to the skin for removal of warts, including plantar warts and genital warts. It is also used topically for white patches on the tongue in people with weakened immune systems (hairy leukoplakia) and for corns.
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