Amniocentesis Risk Overrated?
Miscarriage May Be Rarer Than You Think After Amniocentesis
Nov. 1, 2006 -- Amniocentesis may be even safer than doctors previously
That news comes from a study of about 35,000 U.S. women who were 10 to
nearly 14 weeks pregnant.
The study appears in Obstetrics & Gynecology. The researchers
included Keith Eddleman, MD, of New York's Mount Sinai School of Medicine.
The women were offered amniocentesis, in which doctors insert a thin needle
through the belly to get a small sample of amniotic fluid, which surrounds the
baby in the womb.
The test is used to check the baby's risk for genetic conditions such as
Most of the women -- nearly 32,000 -- declined amniocentesis. About 3,000
About 1% of the women in both groups miscarried before 24 weeks of pregnancy.
The amniocentesis-related miscarriage rate by 24 weeks of
pregnancy was 0.06%, or about one in 1,600 pregnancies studied.
That's lower than the rate of 0.5%, or about one in 200 pregnancies, from
studies done in the 1970s, before current amniocentesis techniques were in
place, the researchers note.
Eddleman commented on the study in a Mount Sinai School of Medicine news
He says women's decisions about amniocentesis "should be based on
contemporary information about miscarriage rates with newer screening
techniques, rather than just relying on general age-based risks."
The findings "will have a significant effect on how women are counseled
about amniocentesis by their doctors and the information they have when
deciding about screening for their unborn child," Eddleman predicts.