Hormones that every woman has in her body -- estrogen and progesterone -- can serve as fuel for some types of breast cancer. They help the cells grow and spread. Hormone therapy, also called endocrine therapy, adds, blocks, or removes those chemicals to treat the disease.
By Amy Engeler
On September 2 of last year, Tomomi Arikawa left her office door open as she slipped out to her two o'clock sonogram appointment. She expected to return shortly — the imaging center was just across town from her office at ABC News, where she was a story editor for 20/20. At her gynecologist's urging, Tomomi was going to have a tender lump in her right breast checked out. The lump felt squishy, like a piece of Bubble Wrap, not like a hard kernel or a marble or any of the objects tumors...
When you’re diagnosed with breast cancer, your doctor will test cells from your tumor to see if they have parts on their surfaces called receptors that use estrogen or progesterone. If they do, it means that they depend on these hormones to grow. In that case, your doctor will probably recommend hormone therapy as part of your treatment plan.
Tamoxifen is a pill that doctors have prescribed for more than 30 years to treat breast cancer. It works by blocking estrogen from attaching to the cancer cells.
Doctors first used tamoxifen to treat women whose breastcancer had spread in their bodies because it slowed or stopped the growth of the disease. The drug also lowers the chance that some early-stage breast cancers will come back. And it can lower the risk that a woman will get cancer in her other breast later on.
Women who are at high risk for breast cancer can take tamoxifen to try to lower their chances of getting the disease. It’s an alternative to watchful waiting or having surgery to remove a breast, called a mastectomy, before they get the disease.