Langerhans Cell Histiocytosis Treatment (PDQ®): Treatment - Patient Information [NCI] - General Information About Langerhans Cell Histiocytosis (LCH)
Certain factors affect prognosis (chance of recovery) and treatment options.
LCH in organs such as the skin, bones, lymph nodes, or pituitary gland usually gets better with treatment and is called "low- risk". LCH in the spleen, liver, or bone marrow is harder to treat and is called "high-risk".
The prognosis (chance of recovery) and treatment options depend on the following:
- How old the patient is when diagnosed with LCH.
- How many body systems the disease affects.
- Whether the disease is found in the liver, spleen, bone marrow, or certain bones in the skull.
- How quickly the disease responds to initial treatment.
- Whether the disease has just been diagnosed or has come back (recurred).
In infants up to one year of age, LCH may go away without treatment.