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'Divine Mix' Prevents Death From Cancer, Heart Disease

June 25, 2003 -- In the largest study ever done on the Mediterranean diet and one of the few to test it in adults of all ages -- in Greece, no less -- researchers found that the real bang of this ballyhooed magic bullet appears not to be olive oil but a combination of all food in the diet.

Scores of studies suggest that the high-fat Mediterranean diet translates to a slimmer risk of heart disease and cancer. And olive oil has sometimes gotten the lion's share of credit -- possibly undeservedly, according to the new findings.

Secret Sauce?

The olive oil-drenched diet is believed to be why residents of the 16 countries that border the Mediterranean Sea typically live longer than Americans and have lower rates of these diseases -- despite consuming a high-fat diet. The theory: Most of the fat comes from monounsaturated fat, the type in olive oil that -- unlike saturated fats -- is heart-healthy and may have cancer-prevention effects.

Not surprisingly, the researchers found that Greeks who follow the Mediterranean diet more closely have significantly lower death and disease rates than those who don't. But they also report in this week's issue of TheNew England Journal of Medicine that olive oil itself produced no significant reduction in overall death rates.

Divine Mix

"Olive oil plays a central role, but it is not alone," says Dimitrios Trichopoulos, MD, PhD, of Harvard School of Public Health.

"It's among the divine mix of several factors that, when used in combination, help provide strong evidence of something that is very important -- eating the proper diet can significantly reduce your risk of early death."

He and researchers from Greece studied some 22,000 adults, aged 20 to 86, from all regions of that country; most previous studies tracked only older people who were more likely to die during the study. The participants answered detailed questionnaires about their eating habits throughout the four-year study. Then they were rated on how closely they followed the key principles of the Mediterranean diet.

Sticking to the Mediterranean diet cut the risk of death from both heart disease and cancer. For every two points higher on this 0-to-9 scale -- with top numbers going to those most closely following the Mediterranean diet -- the death rate dropped by 25%.

So what does that mean exactly? Substantially increasing the intake of monounsaturated fats relative to saturated fats and reducing in intake of meat would do the trick.

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