If you are:
Only When Necessary: NON-TERATOGENIC COMPLICATIONS (RESP, GI,CNS) WITH EXPOSURE DURING 3RD TRIMESTER
Precaution: NO KNOWN INFANT ADV EFFECTS WITH SHORT TERM TX, LONG TERM CNS EFFECTS UNKNOWN
An adult over 60:
management or monitoring precaution: Renal-Recommended dose of 50mg for CrCL=30-50 mL/minute. Endocrine-May exacerbate or cause SIADH or hyponatremia. Monitor sodium level closely when starting or changing dosages in older adults. Cardiovascular-Elderly at increased risk for orthostatic hypotension.
Giving desvenlafaxine ER to a child under 12:
Severe Precaution: Possible increased suicidal ideation and attempt. Not approved for pediatric use.