Although osteoporosis cannot be reversed, it can be prevented and treated in a variety of ways.
There's calcium and vitamin D, both key to bone health. Exercise is another critical part of strengthening bone mass. There are drugs on the market that slow bone loss and even hold promise of building new bone.
If you're one of the 34 million Americans (women and men) who are at risk for the disease, you know that strengthening and protecting your bones is crucial. Osteoporosis means porous bones that weaken and can fracture with even minor incidents.
Some 55% of people 50 and older have osteoporosis or reduced bone mass. But "you can live with osteoporosis for a long, long time and never have complications such as fractures -- if you take certain precautions," says Felicia Cosman, MD, osteoporosis...
Actonel, Binosto, Boniva, and Fosamax (also available as generic) work by inhibiting cells that break down bone and slowing bone loss. Actonel, Binosto, and Fosamax are usually taken once a week, while Boniva is taken once a month. There are strict ways to take these medications, since if taken incorrectly, they can lead to ulcers in the esophagus.
Another osteoporosis medication of the same class is Reclast, which is given as a once-yearly 15-minute infusion in a vein. Reclast is said to increase bone strength and reduce fractures in the hip, spine and wrist, arm, leg, or rib.
Evista is an osteoporosis drug that has some actions similar to estrogen, such as the ability to maintain bone mass. However, studies have shown that it doesn't increase the risk of breast or uterine cancers like estrogen. Evista can cause blood clots and often increases hot flashes.
Forteo is a medication used for the treatment of osteoporosis in postmenopausal women and men who are at high risk for a fracture. A synthetic form of the naturally occurring parathyroid hormone, Forteo is the first drug shown to stimulate new bone formation and increase bone mineral density. It is self-administered as a daily injection for up to 24 months. Side effects include nausea, leg cramps, and dizziness.
Prolia is a monoclonal antibody -- a fully human, lab-produced antibody that inactivates the body's bone-breakdown mechanism. It's the first "biologic therapy" to be approved for osteoporosis treatment. Prolia is approved for postmenopausal women with osteoporosis and high risk of fracture, and when other osteoporosis medicines have not worked.
Menopausal hormone replacement therapy -- either estrogen alone or a combination of estrogen and progestin -- is known to help preserve bone and prevent fractures. The drug Duavee (estrogen and bazedoxifene) is a type of HRT approved to treat menopause-related hot flashes. Duavee may also prevent osteoporosis in high-risk women who have already tried non-estrogen treatment.
HRT is no longer prescribed for osteoporosis alone because of other health risks long-term hormone therapy poses. In women who have been on hormone replacement therapy in the past and then stopped it, the bone begins to thin again -- at the same pace as during menopause.