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FDA Approves Prostate Cancer Drug

Zytiga Fights Treatment-Resistant Prostate Cancer

Side Effects

Commonly reported side effects of Zytiga included joint swelling or discomfort, low levels of potassium in the blood, fluid retention, usually in the legs and feet, muscle discomfort, hot flashes, diarrhea, and urinary tract infection.

Other side effects included cough, high blood pressure, heartbeat disorders, urinary frequency, increased nighttime urination, upset stomach or indigestion, and upper respiratory tract infection.

Centocor, based in Horsham, Pa., says in a statement that the FDA’s approval of Zytiga represents a step forward in the treatment of metastatic prostate cancer.

“As a clinician, I believe the efficacy and safety profile of abiraterone acetate, as well as its oral, once-daily formulation, will help address the important need for additional therapeutic choices for men living with this serious disease,” Howard Scher, MD, of Memorial Sloan-Kettering Cancer Center in New York, says in the company’s news release.

Johann S. de Bono, MD, PhD, MSc, FRCP, of the Royal Marsden NHS Foundation Trust in London, says in the company’s statement that the approval of the drug marks “an exciting time for men with prostate cancer.”

The drug’s approval also was praised in the company’s statement by Wendy L. Poage, MHA, president of the Colorado-based Prostate Conditions Education Council.

Prostate cancer forms in tissues of the prostate, a gland in the male reproductive system below the bladder, and usually occurs in older men, according to the National Cancer Institute (NCI). The NCI says 217,730 new cases of the disease were reported in 2010 and 32,050 men died of prostate cancer.

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