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Hair Loss: Glossary

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Dutasteride: A 5-alpha-reductase inhibitor medication by GlaxoSmithKline. Dutasteride inhibits both type-I and type-II 5-alpha reductase.

Epidermis: The outer protective, nonvascular layer of the skin

Estrogen: The female hormone secreted primarily by the ovaries.

Female Pattern Baldness (FPB): Progressive thinning of hair throughout the entire head caused by genes, age, and hormones. It usually develops at a much slower rate than male pattern baldness.

5-Alpha-Reductase: The chemical that is responsible for transforming testosterone into dihydrotestosterone.

5-Alpha-Reductase Inhibitors: Prevent the body from converting testosterone to dihydrotestosterone by blocking the action of the enzyme 5-alpha reductase.

Finasteride: The generic name of the brand name drug Proscar. Proscar is manufactured by Merck and is FDA approved for the treatment of benign prostate enlargement. 1mg tablets of finasteride have been marketed under the brand name Propecia as a treatment for hair loss. It is an antiandrogen that blocks the formation of dihydrotestosterone by inhibiting the enzyme 5-alpha reductase.

Flap: A type of hair replacement surgery in which a piece of hair-bearing scalp is cut on three or four sides and transplanted onto bald areas of the scalp. Follicle: A saclike structure just below the surface of your scalp. It is the sheath within which hair grows.

Follicular Unit: Natural groupings of hair that grow together as a group in the scalp and share the same blood supply.

Follicular Unit Extraction (FUE): Modification of the standard follicular unit transplant where follicular units are removed individually from the donor area.

Follicular Unit Transplantation: An advanced form of hair transplantation in which the surgeon harvests hair in naturally occurring follicular units and grafts them to balding sections of the scalp.

Free Flap: A surgical procedure in which a wide strip of scalp from the side/back of the head is excised and then transferred to the frontal area of the scalp to form a hairline.

Frontal Alopecia: Hair loss at the front of the head.

Gene Therapy: A treatment method that involves the manipulation of an individual's genetic makeup. It attempts to fix the defective gene which is causing the disease.

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