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INOSITOL

Other Names:

1,2,3,4,5,6-Cyclohexanehexol, 1,2,5/3,4,6-inositol, (1S)-inositol, (1S)-1,2,4/3,5,6-inositol, Antialopecia Factor, (+)-chiroinositol, cis-1,2,3,5-trans-4,6-Cyclohexanehexol, Cyclohexitol, Dambrose, D-chiro-inositol, D-Myo-Inositol, Facteur Anti-...
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Vitamin B8 (INOSITOL) Overview
Vitamin B8 (INOSITOL) Uses
Vitamin B8 (INOSITOL) Side Effects
Vitamin B8 (INOSITOL) Interactions
Vitamin B8 (INOSITOL) Dosing
Vitamin B8 (INOSITOL) Overview Information

Inositol is a vitamin-like substance. It is found in many plants and animals. It can also be made in a laboratory.

Inositol is used for diabetic nerve pain, panic disorder, high cholesterol, insomnia, cancer, depression, schizophrenia, Alzheimer’s disease, attention deficit-hyperactivity disorder (ADHD), autism, promoting hair growth, a skin disorder called psoriasis, and treating side effects of medical treatment with lithium.

Inositol is also used by mouth for treating conditions associated with polycystic ovary syndrome, including failure to ovulate; high blood pressure; high triglycerides; and high levels of testosterone.

How does it work?

Inositol might balance certain chemicals in the body to possibly help with conditions such as panic disorder, depression, obsessive-compulsive disorder, and polycystic ovary syndrome.

Vitamin B8 (INOSITOL) Uses & Effectiveness What is this?

Possibly Effective for:

  • Panic disorder. Inositol shows some promise for controlling panic attacks and the fear of public places or open spaces (agoraphobia). One study found that inositol is as effective as a prescription medication. However, large-scale clinical trials are needed before inositol’s effectiveness for panic attacks can be proven.
  • Obsessive-compulsive disorder (OCD). There is some evidence that people with OCD who receive inositol by mouth for 6 weeks experience significant improvement.
  • An ovary disorder known as polycystic ovary syndrome (PCOS). Taking a particular form of inositol (isomer D-chiro-inositol) by mouth seems to lower triglyceride and testosterone levels, modestly decrease blood pressure, and promote ovulation in obese women with polycystic ovary syndrome.
  • Problems breathing in premature infants known as “acute respiratory distress syndrome,” when given intravenously (by IV).
  • Psoriasis brought on or made worse by lithium drug therapy. Inositol doesn’t seem to help psoriasis in people not taking lithium.

Possibly Ineffective for:

  • Schizophrenia.
  • Alzheimer’s disease.
  • Autism.
  • Depression. Limited research suggests that depressed people receiving inositol for 4 weeks may improve at first, but then get worse again after awhile. There was also some expectation that inositol might make antidepressant medications called SSRIs work better. But research so far hasn’t shown this to be true.

Likely Ineffective for:


Insufficient Evidence for:

  • Attention deficit-hyperactivity disorder (ADHD). Early studies suggest inositol might not help improve ADHD symptoms.
  • Cancer.
  • Hair growth.
  • Problems metabolizing fat.
  • High cholesterol.
  • Trouble sleeping (insomnia).
  • Other conditions.
More evidence is needed to rate inositol for these uses.


Vitamin B8 (INOSITOL) Side Effects & Safety

Inositol is POSSIBLY SAFE for most adults. It can cause nausea, tiredness, headache, and dizziness.

Inositol is POSSIBLY SAFE when used in the hospital for premature infants with acute respiratory distress syndrome.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Not enough is known about the use of inositol during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Bipolar disorder: There is some concern that taking too much inositol might make bipolar disorder worse. There is a report of a man with controlled bipolar disorder being hospitalized with extreme agitation and impulsiveness (mania) after drinking several cans of an energy drink containing inositol, caffeine, taurine, and other ingredients (Red Bull Energy Drink) over a period of 4 days. It is not known if this is related to inositol, caffeine, taurine, a different ingredient, or a combination of the ingredients.

Vitamin B8 (INOSITOL) Interactions What is this?

We currently have no information for Vitamin B8 (INOSITOL) Interactions

Vitamin B8 (INOSITOL) Dosing

The following doses have been studied in scientific research:

BY MOUTH:

  • For panic disorder: 12 to 18 grams per day.
  • For obsessive-compulsive disorder: inositol 18 grams per day.
  • For treating symptoms associated with polycystic ovary syndrome: D-chiro-inositol 1200 mg per day.
  • For treating lithium-related psoriasis: 6 grams daily.

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Conditions of Use and Important Information: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. © Therapeutic Research Faculty 2009.

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