Vulvar Cancer Directory
Vulvar cancer is a rare disease in which cancer cells form in the tissues of the vulva -- usually in the outer lips of the vagina. Human papillomavirus (HPV) infection and older age can increase the risk of developing vulvar cancer. Possible signs include bleeding or itching, a lump in the vulva, and tenderness in the vulvar area. Follow the links below to find WebMD's comprehensive coverage about vulvar cancer, how it develops, its symptoms, treatment, and much more.
Vulvar Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI]-Stage Information for Vulvar Cancer
The diagnosis of vulvar cancer is made by biopsy. The patient may be examined under anesthesia. Cystoscopy, proctoscopy, x-ray examination of the lungs, and intravenous urography (as needed), are used for staging purposes. Suspected bladder or rectal involvement must be confirmed by biopsy. The staging system does not apply to malignant melanoma of the vulva, which is staged like melanoma of the skin.Definitions: FIGOThe Fédération Internationale de Gynécologie et d'Obstétrique (FIGO) and the American Joint Committee on Cancer (AJCC) have designated staging to define vulvar cancer; the FIGO system is most commonly used.[1,2] Stage is based upon pathology staging at the time of surgery or prior to any radiation or chemotherapy, if they are the initial treatment modalities.Table 1. Carcinoma of the Vulvaaa Adapted from FIGO Committee on Gynecologic Oncology.b The depth of invasion is defined as the measurement of the tumor from the epithelial-stromal junction of
Vulvar Cancer Treatment (PDQ®): Treatment - Patient Information [NCI]-Treatment Options for Recurrent Vulvar Cancer
Treatment of recurrent vulvar cancer may include the following:Wide local excision with or without radiation therapy to treat cancer that has come back in the same area.Radical vulvectomy and pelvic exenteration to treat cancer that has come back in the same area.Chemotherapy and radiation therapy with or without surgery.Radiation therapy followed by surgery or chemotherapy.Radiation therapy as palliative treatment to relieve symptoms and improve quality of life.A clinical trial of a new treatment.Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with recurrent vulvar cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.
Vulvar Cancer Treatment (PDQ®): Treatment - Patient Information [NCI]-Treatment Options by Stage
A link to a list of current clinical trials is included for each treatment section. For some types or stages of cancer, there may not be any trials listed. Check with your doctor for clinical trials that are not listed here but may be right for you.Vulvar Intraepithelial Neoplasia (VIN)Treatment of vulvar intraepithelial neoplasia (VIN) may include the following:Removal of single lesions or wide local excision.Laser surgery.Ultrasound surgical aspiration.Skinning vulvectomy with or without a skin graft.Biologic therapy with topical imiquimod.Stage I Vulvar CancerTreatment of stage I vulvar cancer may include the following:Wide local excision for lesions that are less than 1 millimeter deep..Radical local excision and removal of nearby lymph nodes.Radical local excision and sentinel lymph node biopsy. If cancer is found in the sentinel lymph node, nearby lymph nodes are also removed.Radiation therapy for patients who cannot have surgery.Check for U.S. clinical trials from NCI's list of
Vulvar Cancer Treatment (PDQ®): Treatment - Patient Information [NCI]-Treatment Option Overview
There are different types of treatment for patients with vulvar cancer.Different types of treatments are available for patients with vulvar cancer. Some treatments are standard (the currently used treatment), and some are being tested in clinical trials. A treatment clinical trial is a research study meant to help improve current treatments or obtain information on new treatments for patients with cancer. When clinical trials show that a new treatment is better than the standard treatment, the new treatment may become the standard treatment. Patients may want to think about taking part in a clinical trial. Some clinical trials are open only to patients who have not started treatment. Four types of standard treatment are used:SurgerySurgery is the most common treatment for vulvar cancer. The goal of surgery is to remove all the cancer without any loss of the woman's sexual function. One of the following types of surgery may be done:Laser surgery: A surgical procedure that uses a laser
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