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How is valproate (Depakote) used to treat bipolar I disorder?

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This anti-seizure medication also works to level out moods. It is faster acting than lithium for an acute episode of mania. It is also often used "off-label" for prevention of new episodes. As a mood stabilizer that can be used by a "loading dose" method -- beginning at a very high dose -- valproate allows the possibility of significant improvement in mood as early as four to five days.

From: Bipolar I Disorder WebMD Medical Reference

SOURCES: Moore, D. Mosby, 2004. National Institute of Mental Health web site: "Bipolar Disorder."  Medical News Today: "Study Identifies Predictors Of Bipolar Disorders Risk." WebMD Medical Reference from Healthwise: "Bipolar Disorder -- What Increases Your Risk." Sunovion Pharmaceuticals, Inc.




Handbook of Medical Psychiatry,

Reviewed by Smitha Bhandari on November 08, 2017

SOURCES: Moore, D. Mosby, 2004. National Institute of Mental Health web site: "Bipolar Disorder."  Medical News Today: "Study Identifies Predictors Of Bipolar Disorders Risk." WebMD Medical Reference from Healthwise: "Bipolar Disorder -- What Increases Your Risk." Sunovion Pharmaceuticals, Inc.




Handbook of Medical Psychiatry,

Reviewed by Smitha Bhandari on November 08, 2017

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What other mood stabilizers are used to treat bipolar I disorder?

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