The Role of Cholesterol
Researchers don't know exactly what causes Alzheimer's disease. But substances found in the brains of people with Alzheimer's, called amyloid plaques, may be part of it.
In a recent study, Charles DeCarli, MD, director of the University of California, Davis Alzheimer's Disease Research Center, and colleagues looked at levels of amyloid in the brains of 74 older adults.
"Unhealthy patterns of cholesterol could be directly causing the higher levels of amyloid known to contribute to Alzheimer's, in the same way that such patterns promote heart disease," says Bruce Reed, MD, a study researcher and a co-director of the UC-Davis Alzheimer's Center.
The study, the first to link cholesterol to amyloid plaques in the brain, doesn't directly say whether or not cholesterol is a risk for dementia, DeCarli says.
"We primarily looked at people who did not have dementia. There are still a lot of questions. But now that we have this amyloid imaging tool, we can actually ask those questions and identify relationships we couldn't see before."
Improving Your Cholesterol Numbers
This could potentially make a big difference in reducing the number of people with Alzheimer's, Reed says.
What's clear, DeCarli says, is that if you're at risk for heart disease because your cholesterol levels aren't right, you have one more reason not to ignore the numbers. Your risk of Alzheimer’s might be less after cholesterol treatment.