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High: Makes You Pee More

Your kidneys have to work hard to process all that extra sugar in your blood. When they can’t keep up, your body gets rid of it, along with water that your body needs.   

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mature man drinking water
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High: Makes You Thirsty

To get rid of that extra sugar, your body draws water from its own tissues. Because you need that fluid to make energy, transfer nutrients, and get rid of waste, a switch flips in your brain to tell you that you’re thirsty so you’ll drink more.

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dry lips
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High: Dry Mouth

Your mouth could get dry and cracked at the corners as your body draws fluid from it. Less saliva and more sugar in your blood make infection more likely. Your gums might swell, and white patches can grow on your tongue and inside your cheeks (your doctor will call this oral thrush). It can help to drink more water or chew sugar-free gum.

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cracked heels
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High: Skin Problems

Your body takes water from all over to get rid of extra blood sugar. That may cause dry, itchy, cracked, skin, especially on your legs, elbows, feet, and hands. In time, high glucose levels also can damage nerves. This is called diabetic neuropathy. It can make it harder for you to feel cuts, wounds, or infections. Without treatment, they can become bigger problems, like the loss of a toe, foot, or part of your leg. 

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blurry vision
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High: Vision Problems

Your body may pull fluid from the lenses in your eyes, which makes it harder to focus. And high blood sugar can damage blood vessels on the back part of your eye (retina). That can cause long-term vision loss and even blindness. 

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woman with fatigue
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High: Fatigue

When you have type 2 diabetes and your blood sugar is high too often, you become less sensitive to insulin, which helps move energy to your cells. A lack of fuel can make you tired. You can have the same fatigue with type 1 diabetes, because your body can’t make its own insulin. If you don’t treat it correctly, your levels can stay high all the time. Your doctor can help by prescribing medication and suggesting lifestyle changes you can make.

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woman sleeping with dog
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Low: Fatigue

If you have diabetes, insulin is one way to lower your blood sugar when it gets high. But if you take too much, it might remove so much glucose so quickly that your body can’t replace it fast enough. That leaves you tired. Other illnesses and drugs also may also upset this cycle and empty your tank.

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vagus nerve
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High: Digestive Problems

If your blood sugar is high for too long, it can damage the vagus nerve, which helps move food through your stomach and intestines. You may lose weight because you aren’t as hungry. You might have trouble with acid reflux, cramps, vomiting, and severe constipation.

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Low: Weird Heartbeat

The hormones that help raise your blood sugar when it’s too low can also spike your heart rate and make it feel like it skips a beat. (Your doctor will call this arrhythmia.) The drop in glucose most often happens as a side effect of drugs used to treat diabetes.

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Low: Shakiness

Low glucose can unsettle your central nervous system, which controls how you move. When that happens, your body releases hormones, like adrenaline, to help bring your levels back up. But those same substances also may make your hands and other parts shake or tremble.

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Low: Sweaty

The hormones your body releases to raise your blood sugar when it gets too low also make you sweat a lot. It’s often one of the first things you notice when your glucose levels fall too far. Your doctor can help you track your levels and try to keep them in a healthy range with medication, exercise, and eating habits.

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woman looking in fridge
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Low: Hungry

Sudden, intense hunger, even after you’ve eaten, may be a sign that your body doesn’t convert food to blood sugar in the right way. Illness or certain drugs can cause it, too. If you have diabetes, your doctor might be able to adjust your medication, which is often the source of the problem. 

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woman with nausea
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Low: Nausea

Actually, it isn’t low blood sugar by itself. When your levels get either very high or very low, it can cause a rebound effect. Your blood sugar bounces from one extreme to the other, confuses your body’s digestive system, and makes you feel sick to your stomach. 

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spinning trees
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Low: Dizziness

Your brain cells need glucose to work properly. When they don’t have enough, you may start to feel tired, weak, and dizzy. You also might have a headache.

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mature man confused
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Low: Confusion

When your blood sugar gets really low (hypoglycemia), you start to lose your bearings. You may slur your speech or forget where you are. Sometimes it happens so suddenly that you might not even realize you’re acting strangely. In serious cases, you could have a seizure or fall into a coma.

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Sources | Medically Reviewed on 06/06/2020 Reviewed by Michael Dansinger, MD on June 06, 2020


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Mayo Clinic: “Diabetes symptoms: When diabetes symptoms are a concern,” “Hypoglycemia,” “Type 1 diabetes.”

Diabetes.co.uk: “Diabetes and Skin Care,” “Dizziness,” “Dry Mouth and Diabetes,” “Nausea and Vomiting,” “Extreme Tiredness (Fatigue).”

NIH National Institute of Diabetes and Digestive and Kidney Diseases: “Peripheral Neuropathy.”

NIH National Eye Institute: “Facts About Diabetic Eye Disease.”

American Diabetes Association: “Gastroparesis,” “More on the Mouth.”

Diabetes Care: “Hypoglycemia and Cardiovascular Risks.”

Cleveland Clinic: “Low Blood Sugar? 8 Warning Signs if You Have Diabetes.”

Nemours Foundation: “What Is Hypoglycemia?”

Merck Manuals Consumer Version: “Hypoglycemia.”

Reviewed by Michael Dansinger, MD on June 06, 2020

This tool does not provide medical advice. See additional information.

THIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. It is intended for general informational purposes only and does not address individual circumstances. It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. Never ignore professional medical advice in seeking treatment because of something you have read on the WebMD Site. If you think you may have a medical emergency, immediately call your doctor or dial 911.