What should I Know Regarding Pregnancy, Nursing and Administering Crizotinib Capsule to Children or the Elderly?
If you are PREGNANT
- Not Recommended: INSUFFICIENT HUMAN DATA AVAIL; CONSIDER MATERNAL BENEFIT VS FETAL/NEONATAL RISK
If you are NURSING
- Absolute Contraindication: POTENTIALLY HARMFUL TO INFANT BASED ON MECHANISM OF ACTION
If you are an adult over 60
- management or monitoring precaution: Cardiovascular-May cause bradycardia. Elderly may be more susceptible to QT prolongation. Caution with concomitant bradycardia, electrolyte disturbance or underlying cardiac arrhythmia. Hepatic-Rare risk of fatal hepatotoxicity. Monitor hepatic function. Vision-Use caution in the elderly with vision impairment due to risk for bilateral visual field impairment.
Giving Crizotinib Capsule to a child under 12
- Severe Precaution: Potential for decreased bone formation. No safety and efficacy established.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.