Who should not take ICLUSIG?

The following conditions are contraindicated with this drug. Check with your physician if you have any of the following:


  • anemia
  • decreased blood platelets
  • low levels of a type of white blood cell called neutrophils
  • high blood pressure
  • a heart attack
  • acute blood clot in the heart
  • coronary artery disease
  • slow heartbeat
  • supraventricular arrhythmias, a type of abnormal heart rhythm
  • chronic heart failure
  • sudden and serious symptoms of heart failure called acute decompensated heart failure
  • a blood clot in the brain
  • a stroke
  • a localized weakening and ballooning in an artery wall called an arterial aneurysm
  • obstruction of a blood vessel by a blood clot
  • a blood clot in an artery
  • peripheral vascular disease
  • blood clot formation in vein
  • bleeding
  • blockage or closing off of blood vessels
  • damage to the liver and inflammation
  • recent operation
  • visible water retention
  • abnormal liver function tests
  • impaired wound healing
  • pregnancy
  • a mother who is producing milk and breastfeeding
  • a rupture in the wall of the stomach or intestine
  • reactivation of hepatitis B infection
  • pancreatitis
  • a type of brain disorder called posterior reversible encephalopathy syndrome
  • dissection of artery
Drug Survey

Are you currently using ponatinib oral?

This survey is being conducted by the WebMD marketing sciences department.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.