GILOTRIF Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • abnormal liver function tests

If experienced, these tend to have a Less Severe expression i

  • stomatitis, a condition with painful swelling and sores inside the mouth
  • inflammation and infection of nail cuticle
  • erythema or redness of skin or mucous membrane
  • itching
  • a skin rash resembling acne
  • dry skin
  • a skin rash
  • decreased appetite
  • nausea
  • vomiting
  • diarrhea

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • dehydration
  • anemia
  • low levels of white blood cells
  • left ventricular heart failure
  • depression of the function of the heart
  • erythrodysesthesia or tingling, pain, redness, and edema in the hands and feet
  • excessive diarrhea
  • a rupture in the wall of the stomach or intestine
  • lung tissue problem
  • cellulitis
  • a high alanine transaminase level

If experienced, these tend to have a Less Severe expression i

  • pink eye
  • inflammation of the eyelid
  • throat irritation
  • a common cold
  • inflammation of the lips
  • a painful, red or swollen tongue
  • gastroesophageal reflux disease
  • a type of stomach irritation called gastritis
  • constipation
  • soreness of the rectal area
  • a nail disorder
  • hair loss
  • hirsutism, a condition of hair growth on parts of the body normally without hair
  • darkening of the skin
  • joint pain
  • backache
  • muscle spasm
  • muscle pain
  • dizziness
  • fever
  • weight loss
  • headache
  • nosebleed
  • cough
  • difficulty swallowing
  • abdominal bloating
  • abnormal sensations of the skin
  • runny nose
  • intense abdominal pain
  • pain in the muscles or bones

RARE side effects

If experienced, these tend to have a Severe expression i

  • a systemic inflammatory response called sepsis due to an infection with bacteria
  • low amount of potassium in the blood
  • inflammation of the cornea of the eye
  • pneumonia
  • inflammation in the lungs due to an allergic reaction
  • a type of inflammation of the lung called interstitial pneumonitis
  • lung failure causing loss of breath
  • liver failure
  • inflammation of the skin with blisters
  • a skin disorder with blistering and peeling skin called toxic epidermal necrolysis
  • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
  • skin rash with sloughing
  • trouble breathing
  • pancreatitis

If experienced, these tend to have a Less Severe expression i

  • low energy

Free RX Coupon

Save up to 80% on your prescriptions.

Available coupons

Save up to 80% on your prescription with WebMDRx

Drug Survey

Are you currently using afatinib oral?

This survey is being conducted by the WebMD marketing sciences department.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.