Does PREZCOBIX Interact with other Medications?

Severe Interactions

These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • SELECTED PROTEASE INHIBITORS/BEPRIDIL
  • SELECTED CYP3A4 INHIBITORS/CISAPRIDE
  • SELECTED CYP3A4 INHIBITORS/PIMOZIDE
  • PROTEASE INHIBITORS/ERGOT ALKALOIDS
  • PROTEASE INHIBITORS/ASTEMIZOLE; TERFENADINE
  • SELECTED PROTEASE INHIBITORS; COBICISTAT/CYP3A4 INDUCERS
  • STRONG CYP3A4 INHIBITORS/MAVACAMTEN
  • STRONG CYP3A4 INHIBITORS/PACRITINIB
  • SELECTED STRONG CYP3A4 INHIBITORS/CONIVAPTAN
  • SELECTED STRONG CYP3A4 INHIBITORS/ALFUZOSIN
  • STRONG CYP3A4 INHIBITORS/FINERENONE
  • STRONG CYP3A4 INHIBITORS/VOCLOSPORIN
  • STRONG AND MODERATE CYP3A4 INHIBITORS/LONAFARNIB
  • COBICISTAT/DABIGATRAN
  • STRONG CYP3A4 INHIBITORS/UBROGEPANT
  • SELECTED STRONG CYP3A4 INHIBITORS/ALPRAZOLAM; TRIAZOLAM
  • STRONG CYP3A4 INHIBITORS; ATAZANAVIR;DARUNAVIR/LERCANIDIPINE
  • SLT STRONG & MODERATE CYP3A4 INHIBITORS/CILOSTAZOL (>50MG)
  • STRONG CYP3A4 INHIBITORS/DAPAGLIFLOZIN-SAXAGLIPTIN-METFORMIN
  • STRONG AND MODERATE CYP3A4 INHIBITORS/ASUNAPREVIR
  • DARUNAVIR-COBICISTAT/ROSUVASTATIN (> 20 MG)
  • STRONG OR MODERATE CYP3A4 INHIBITORS/LOMITAPIDE
  • OATP1B1-3 INHIBITORS/ELBASVIR-GRAZOPREVIR
  • SELECTED STRONG CYP3A4 INHIBITORS/ISAVUCONAZONIUM
  • STRONG CYP3A4 INHIBITORS/PANOBINOSTAT (> 10 MG)
  • STRONG CYP3A4 INHIBITORS/NALOXEGOL
  • STRONG CYP3A4 INHIBITORS/AVANAFIL
  • 3A4INHIB/DAPOXETINE;LEVOMILNACIPRAN(>80MG);VILAZODONE(>20MG)
  • STRONG OR MODERATE CYP3A4 INHIBITORS/FLIBANSERIN
  • PROTEASE INHIBITORS & NNRTIS/COBICISTAT-ELVITEGRAVIR
  • STRONG CYP3A4 INHIBITORS/SLT HIGH STRENGTH ANTIMUSCARINICS
  • DARUNAVIR; FOSAMPRENAVIR; SAQUINAVIR/ATORVASTATIN (>20 MG)
  • SELECTED CYP3A4 INHIBITORS/ORAL MIDAZOLAM
  • STRONG CYP3A4 INHIBITORS; PROTEASE INHIBITORS/TICAGRELOR
  • SELECTED PROTEASE INHIBITORS; COBICISTAT/LURASIDONE
  • HIV PROTEASE INHIBITORS; COBICISTAT/SILDENAFIL (FOR PAH)
  • STRONG CYP3A4 INHIB;ATAZANAV;DARUNAVIR/SAXAGLIPTIN (>2.5 MG)
  • STRONG CYP3A4 INHIBITORS; ATAZANAVIR; DARUNAVIR/DRONEDARONE
  • P-GP AND STRONG CYP3A4 INHIBITORS/RIVAROXABAN
  • STRONG CYP3A4 INHIBITORS; PROTEASE INHIBITORS/RANOLAZINE
  • STRONG CYP3A4 INHIBITORS/TOLVAPTAN
  • STRONG CYP3A4 INHIBITORS; PROTEASE INHIBITORS/IVABRADINE
  • STRONG CYP3A4 INHIBITORS/SILODOSIN; TAMSULOSIN
  • STRONG CYP3A4 INHIBITORS/EPLERENONE
  • STRONG CYP3A4 INHIBITORS/IRINOTECAN
  • SELECTED PROTEASE INHIBITORS; COBICISTAT/ELETRIPTAN
  • SELECTED CYP3A4 INHIBITORS/LOVASTATIN; SIMVASTATIN
  • STRONG CYP3A4 INHIBITORS/VARDENAFIL (>2.5 MG)
  • Serious Interactions

    These medications may interact and cause very harmful effects. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • SELECTED PROTEASE INHIBITORS/ALPRAZOLAM
  • SELECTED PROTEASE INHIBITORS/CONTRACEPTIVES
  • SELECTED PROTEASE INHIBITORS/RIFABUTIN; RIFAPENTINE
  • SELECTED PROTEASE INHIBITORS/GARLIC
  • DARUNAVIR/LOPINAVIR; SAQUINAVIR; OMBITAS-PARITAP-RITONAVIR
  • COBICISTAT-BOOSTED DARUNAVIR/EFAVIRENZ;ETRAVIRINE;NEVIRAPINE
  • COBICISTAT/TENOFOVIR DISOPROXIL
  • SLT SENSITIVE 3A4 SUBSTRATES THAT INHIBIT 3A4/ORAL LEFAMULIN
  • SELECTED PROTEASE INHIBITORS/VONOPRAZAN-CLARITHROMYCIN
  • MODERATE CYP3A4 INHIBITORS/PACRITINIB
  • STRONG CYP3A4 INHIBITORS/MITAPIVAT
  • STRONG CYP3A4 INHIBITOR/TOLTERODINE (>1 MG IR OR >2 MG ER)
  • STRONG CYP3A4 INHIBITORS/RIVOCERANIB
  • STRONG CYP3A4 INHIBITORS/DARIDOREXANT
  • STRONG CYP3A4 INHIBITORS/LEVOKETOCONAZOLE
  • STRONG CYP3A4 INHIBITORS/UPADACITINIB (>=30 MG)
  • STRONG CYP3A4 INHIBITORS/RUPATADINE
  • STRONG CYP3A4 INHIBITORS/AVACOPAN
  • STRONG CYP3A4 INHIBITORS/MOBOCERTINIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/FEXINIDAZOLE
  • OATP1B1-3 INHIBITORS/BRINCIDOFOVIR
  • STRONG AND MODERATE CYP3A4 INHIBITORS/INFIGRATINIB
  • SELECTED PROTEASE INHIBITORS/FLECAINIDE; PROPAFENONE
  • DUAL STRONG CYP3A4 INHIBITOR & P-GP INHIBITORS/TEPOTINIB
  • MODERATE CYP3A4 INHIBITORS/VOCLOSPORIN
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/RELUGOLIX
  • STRONG CYP3A4 INHIBITORS/TOREMIFENE
  • STRONG CYP3A4 INHIBITORS/SUNITINIB
  • STRONG CYP3A4 INHIBITORS/PAZOPANIB
  • STRONG CYP3A4 INHIBITORS/NILOTINIB
  • STRONG CYP3A4 INHIBITORS/LAPATINIB
  • STRONG CYP3A4 INHIBITORS/DASATINIB
  • STRONG CYP3A4 INHIBITORS/CRIZOTINIB
  • STRONG CYP3A4 INHIBITORS/CERITINIB
  • STRONG CYP3A4 INHIBITORS/VINFLUNINE
  • STRONG CYP3A4 INHIBITORS/VINCRISTINE
  • STRONG CYP3A4 INHIBITORS/VINBLASTINE
  • STRONG CYP3A4 INHIBITORS/TOFACITINIB
  • STRONG CYP3A4 INHIBITORS/SONIDEGIB
  • STRONG CYP3A4 INHIBITORS/RUXOLITINIB
  • STRONG CYP3A4 INHIBITORS/PONATINIB
  • STRONG CYP3A4 INHIBITORS/PALBOCICLIB
  • STRONG CYP3A4 INHIBITORS/PACLITAXEL
  • STRONG CYP3A4 INHIBITORS/OLAPARIB
  • STRONG CYP3A4 INHIBITORS/IXABEPILONE
  • STRONG CYP3A4 INHIBITORS/IDELALISIB
  • STRONG CYP3A4 INHIBITORS/ERLOTINIB
  • STRONG CYP3A4 INHIBITORS/DOXORUBICIN
  • STRONG CYP3A4 INHIBITORS/DOCETAXEL
  • STRONG CYP3A4 INHIBITORS/DABRAFENIB
  • STRONG CYP3A4 INHIBITORS/COBIMETINIB
  • STRONG CYP3A4 INHIBITORS/CABOZANTINIB
  • STRONG CYP3A4 INHIBITORS/CABAZITAXEL
  • STRONG CYP3A4 INHIBITORS/AXITINIB
  • STRONG CYP3A4 INHIBITORS/SUVOREXANT
  • STRONG CYP3A4 AND P-GP INHIBITORS/PRALSETINIB
  • STRONG CYP3A4 INHIBITORS/PLITIDEPSIN
  • STRONG AND MODERATE CYP3A4 INHIBITORS/LURBINECTEDIN
  • MODERATE CYP3A4 INHIBITORS/SELPERCATINIB
  • STRONG CYP3A4 INHIBITORS/SELPERCATINIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/PEMIGATINIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/SELUMETINIB
  • STRONG CYP3A4 INHIBITORS/RIMEGEPANT
  • STRONG CYP3A4 INHIBITORS/NIMODIPINE
  • STRONG CYP3A4 INHIBITORS/TAZEMETOSTAT
  • STRONG CYP3A4 INHIBITORS/AVAPRITINIB
  • SELECTED CYP3A4 INHIBITORS/FLUTICASONE-SALMETEROL
  • STRONG AND MODERATE CYP3A4 INHIBITORS/LUMATEPERONE
  • STRONG AND MODERATE CYP3A4 INHIBITORS/LEMBOREXANT
  • STRONG CYP3A4 INHIBITORS/ELEXACAFTOR-TEZACAFTOR-IVACAFTOR
  • STRONG CYP3A4 INHIBITORS/NALDEMEDINE
  • STRONG CYP3A4 INHIBITORS/ISTRADEFYLLINE
  • SELECTED STRONG CYP3A4 INHIBITORS/ORAL LEFAMULIN
  • STRONG CYP3A4 INHIBITORS/FEDRATINIB
  • MODERATE CYP3A4 INHIBITORS/ENTRECTINIB
  • STRONG CYP3A4 INHIBITORS/ENTRECTINIB
  • STRONG CYP3A4 INHIBITORS/PEXIDARTINIB
  • STRONG CYP3A4 INHIBITORS/BOSUTINIB
  • SELECTED PROTEASE INHIBITORS; COBICISTAT/CLOPIDOGREL
  • PROTEASE INHIBITORS/QUETIAPINE
  • STRONG CYP3A4 INHIBITORS/LAROTRECTINIB
  • STRONG CYP3A4 INHIBITORS/GLASDEGIB
  • STRONG CYP3A4 INHIBITORS/LORLATINIB
  • WEAK CYP2D6 INHIBITORS/ELIGLUSTAT
  • STRONG CYP3A4 INHIBITORS/DUVELISIB
  • STRONG CYP3A4 INHIBITORS/ELAGOLIX
  • SELECTED STRONG CYP3A4 INHIBITORS/IVOSIDENIB
  • STRONG CYP3A4 INHIBITORS/ARIPIPRAZOLE LAUROXIL SUBMICRONIZED
  • STRONG AND MODERATE CYP3A4 INHIBITORS/ENCORAFENIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/TEZACAFTOR-IVACAFTOR
  • SELECTED INHIBITORS OF BCRP/CLADRIBINE
  • SELECTED STRONG CYP3A4 INHIBITOR;PROTEASE INHIB/DISOPYRAMIDE
  • STRONG CYP3A4 INHIBITORS/IBRUTINIB
  • STRONG CYP3A4 INHIBITORS/ACALABRUTINIB
  • STRONG CYP3A4 INHIBITORS/ABEMACICLIB
  • STRONG CYP3A4 INHIBITORS/COPANLISIB
  • DARUNAVIR; LOPINAVIR; RITONAVIR/GLECAPREVIR-PIBRENTASVIR
  • STRONG CYP3A4 INHIB;MODERATE 3A4 & P-GP DUAL INHIB/NERATINIB
  • STRONG CYP3A4 INHIBITORS/BRIGATINIB
  • STRONG CYP3A4 INHIBITORS/VALBENAZINE
  • STRONG CYP3A4 INHIBITORS/RIBOCICLIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/DEFLAZACORT
  • STRONG CYP3A4 INHIBITORS/PIMAVANSERIN
  • STRONG CYP3A4 INHIBITORS/VENETOCLAX
  • STRONG CYP3A4 INHIBITORS/VEMURAFENIB
  • STRONG CYP3A4 INHIBITORS/TRABECTEDIN
  • STRONG CYP3A4 INHIBITORS/CARIPRAZINE
  • STRONG CYP3A4 INHIB;ATAZANAV;DARUNAVIR/BEDAQUILINE;DELAMANID
  • STRONG CYP3A4 INHIBITORS/TRASTUZUMAB EMTANSINE
  • STRONG 3A4 INHIBITORS/ESZOPICLONE > 2 MG; ZOPICLONE > 5 MG
  • STRONG & MODERATE CYP3A4 INHIBITORS/ELIGLUSTAT
  • STRONG CYP3A4 INHIBITORS/VORAPAXAR
  • STRONG & MODERATE CYP3A4 INHIBITORS/GUANFACINE
  • STRONG OR MODERATE CYP3A4 INHIBITORS/SIMEPREVIR
  • STRONG CYP3A4 INHIBITORS/MACITENTAN
  • P-GP AND STRONG CYP3A4 INHIBITORS/APIXABAN
  • STRONG CYP3A4 INHIBITORS; AMPRENAVIR;ATAZANAVIR/MIFEPRISTONE
  • STRONG AND MODERATE CYP3A4 INHIBITORS/IVACAFTOR
  • SELECTED PROTEASE INHIBITORS/TELAPREVIR
  • SELECTED PROTEASE INHIBITORS/QUININE
  • COBICISTAT; HCV OR HIV PROTEASE INHIBITORS/SALMETEROL
  • PROTEASE INHIBITORS/BOSENTAN
  • STRONG CYP3A4 INHIBITORS/EVEROLIMUS
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/TOPOTECAN
  • SELECTED PROTEASE INHIBITORS/MARAVIROC
  • PROTEASE INH;COBICISTAT/SLT IMMUNOSUPPRESSANTS;TEMSIROLIMUS
  • STRONG CYP3A4 INHIBITORS; ATAZANAVIR/COLCHICINE
  • SELECTED CYP3A4 INHIBITORS/SELECTED OPIOIDS
  • SELECTED CYP3A4 INHIBITORS/TRAZODONE
  • SELECTED CYP3A4 INHIBITORS/SELECTED STEROIDS
  • COBICISTAT; RITONAVIR/VORICONAZOLE
  • Moderate Interactions

    These medications may cause some risk when taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • SELECTED PROTEASE INHIBITORS/DIDANOSINE
  • COBICISTAT; RITONAVIR/TENOFOVIR ALAFENAMIDE (> 10 MG)
  • SELECTED PROTEASE INHIBITORS/NIRMATRELVIR-RITONAVIR
  • STRONG CYP3A4 INHIBITORS/GILTERITINIB
  • MODERATE CYP3A4 INHIBITORS/MITAPIVAT
  • STRONG CYP3A4 INHIBITORS/TOLTERODINE (<=1 MG OR <=2 MG ER)
  • MODERATE CYP3A4 INHIBITORS/DARIDOREXANT
  • STRONG CYP3A4 INHIBITORS/UPADACITINIB (<30 MG)
  • STRONG CYP3A4 INHIBITORS/SURUFATINIB
  • OATP1B1-3 INHIBITORS/ATOGEPANT
  • STRONG CYP3A4 INHIBITORS/ATOGEPANT
  • STRONG CYP3A4 INHIBITORS/IBREXAFUNGERP
  • STRONG CYP3A4 INHIBITORS/REPAGLINIDE
  • PROTEASE INHIBITORS/SELECTED BENZODIAZEPINES
  • STRONG CYP2D6 OR CYP3A4 INHIBITORS/OLICERIDINE
  • STRONG CYP3A4 INHIBITORS/FOSTAMATINIB
  • STRONG CYP3A4 INHIBITORS/OSILODROSTAT
  • SELECTED STRONG CYP3A4 INHIBITORS/ROMIDEPSIN
  • STRONG CYP3A4 INHIBITORS/CANNABIDIOL-TETRAHYDROCANNABINOL
  • SELECTED STRONG CYP3A4 INHIBITORS/MEFLOQUINE
  • STRONG CYP3A4 INHIBITORS/ZANUBRUTINIB
  • P-GP AND STRONG CYP3A4 INHIBITORS/DAROLUTAMIDE
  • SELECTED STRONG CYP3A4 INHIBITORS/ILOPERIDONE
  • COBICISTAT; TIPRANAVIR/MEXILETINE
  • SELECTED PROTEASE INHIBITORS/LIDOCAINE
  • STRONG CYP3A4 INHIBITORS/BREXPIPRAZOLE
  • COBICISTAT/DIAZEPAM
  • STRONG CYP3A4 INHIBITORS/CLONAZEPAM
  • DARUNAVIR-COBICISTAT/ROSUVASTATIN (< = 20 MG)
  • STRONG CYP3A4 INHIBITORS/MIDOSTAURIN
  • SELECTED CYP3A4 INHIBITORS/FELODIPINE
  • P-GP AND SELECTED CYP3A4 INHIBITORS/NINTEDANIB
  • STRONG 3A4 INHIB/LEVOMILNACIPRAN(<=80MG);VILAZODONE(<=20MG)
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/AFATINIB
  • STRONG CYP3A4 INHIBITORS/REGORAFENIB
  • DARUNAVIR; FOSAMPRENAVIR; SAQUINAVIR/ATORVASTATIN (<= 20 MG)
  • STRONG CYP3A4 INHIBITORS/VARDENAFIL (<=2.5 MG)
  • STRONG CYP3A4 INHIBITORS/PANOBINOSTAT (<= 10 MG)
  • HIV PROTEASE INHIBITORS;COBICISTAT/SILDENAFIL (ED);TADALAFIL
  • STRONG CYP3A4 INHIB;ATAZANAV;DARUNAVIR/SAXAGLIPTIN(<=2.5 MG)
  • SELECTED WEAK CYP2D6 INHIBITORS/TAMOXIFEN
  • DARUNAVIR/PRAVASTATIN
  • CYP3A4; CYP2C8; P-GLYCOPROTEIN (P-GP) INHIBITORS/LOPERAMIDE
  • STRONG CYP3A4 INHIBITORS/BUSPIRONE
  • STRONG CYP3A4 INHIBITORS/ESZOPICLONE; ZOPICLONE; ZOLPIDEM
  • SELECTED CYP3A4 INHIBITORS/ITRACONAZOLE; KETOCONAZOLE
  • STRONG CYP3A4 INHIBITORS/CINACALCET
  • SELECTED PROTEASE INHIBITORS/SELECTED ANTIARRHYTHMICS
  • STRONG CYP3A4 INHIBITORS; ATAZANAVIR; DARUNAVIR/ARIPIPRAZOLE
  • SELECTED STRONG CYP3A4 INHIBITORS/ARTEMETHER;LUMEFANTRINE
  • SELECTED PROTEASE INHIBITORS/CLARITHROMYCIN
  • STRONG CYP3A4 INHIBITORS/SLT LOW STRENGTH ANTIMUSCARINICS
  • SLT STRONG & MODERATE CYP3A4 INHIBITORS/CILOSTAZOL (<=50MG)
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    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.