Warnings:

Panobinostat can cause diarrhea which may become very severe. Tell your doctor right away if you get diarrhea or have abdominal/stomach pain or cramping. Your doctor may need to prescribe medication to stop the diarrhea or stop panobinostat until your diarrhea gets better. Talk to your doctor for more details.

Panobinostat can cause very serious (possibly fatal) heart problems (such as heart attack, irregular heartbeat). Your risk of irregular heartbeat may be increased due to high or low blood mineral levels. Your doctor will monitor your medical and laboratory tests very closely while you are taking this medication. Get medical help right away if you have any signs of heart problems, including: chest/jaw/left arm pain, fast/slow//irregular heartbeat, severe dizziness, fainting (see also Precautions section).

Uses

Panobinostat is used to treat multiple myeloma. It is a chemotherapy drug that works by slowing or stopping the growth of cancer cells.

How to use Panobinostat Capsule

Read the Medication Guide provided by your pharmacist before you start taking panobinostat and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor. It is usually taken once every other day for 3 doses each week for the first 2 weeks, then stopped for 1 week. This is one cycle of treatment. Continue taking the medication this way as directed by your doctor. Swallow the capsules whole with a cup of water. Do not crush, chew, or open the capsules. If you vomit after taking the medication, do not take another dose of the medication that day. Take the next dose at the usual time.

Avoid getting the powder in the capsule onto your skin or into your eyes. If the powder does get onto the skin, wash the area with water and soap. If the powder gets into the eyes, flush the eyes with plenty of water.

The dosage is based on your medical condition, laboratory tests, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Your doctor may stop your medication for a while if you get any side effects. Talk to your doctor for more details.

Avoid eating grapefruit, star fruit, or pomegranate or drinking grapefruit or pomegranate juice while using this medication unless your doctor or pharmacist says you may do so safely. These fruits can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time on the days you are scheduled to take the medication. It may help to mark your calendar with a reminder.

Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of serious side effects will increase.

Since this drug can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication or breathe the powder from the capsules.

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.