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    Spironolactone

    COMMON BRAND NAME(S): Aldactone

    GENERIC NAME(S): Spironolactone

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    Uses

    Spironolactone is used to treat high blood pressure and heart failure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It is also used to treat swelling (edema) caused by certain conditions (such as heart failure, liver disease) by removing excess fluid and improving symptoms such as breathing problems.

    This medication is also used to treat low potassium levels and conditions in which the body is making too much of a natural chemical (aldosterone).

    Spironolactone is known as a "water pill" (potassium-sparing diuretic).

    How to use Spironolactone

    Take this medication by mouth, as directed by your doctor. If stomach upset occurs, take it with food or milk. It is best to take your dose early in the day (before 6 p.m.) to prevent having to get up during the night to urinate. Consult your doctor or pharmacist if you have any questions.

    If you are using the liquid form of this medication, shake the bottle well before each dose. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. You may take the liquid form of this medication with or without food, but it is important to choose one way and take it the same way with every dose.

    Dosage is based on your medical condition and response to therapy. In children, the dosage is also based on body weight.

    Take this medication regularly in order to get the most benefit from it. Remember to use it at the same time(s) each day as directed. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick.

    Take this medication exactly as prescribed. Do not increase your dose, take it more often than prescribed, or stop using this medicine without first consulting your doctor. Your condition may become worse when the drug is suddenly stopped.

    Inform your doctor if your condition worsens (e.g., if you notice an increase in your routine blood pressure readings).

    Side Effects

    Drowsiness, dizziness, lightheadedness, stomach upset, diarrhea, nausea, vomiting, or headache may occur. To minimize lightheadedness, get up slowly when rising from a seated or lying position. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

    Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

    Tell your doctor right away if you have any serious side effects, including: increased thirst, signs of kidney problems (such as change in the amount of urine), mental/mood changes, unusual fatigue/weakness, muscle spasms, menstrual period changes, breast pain, breast enlargement (gynecomastia) in men, sexual function problems, signs of infection (e.g., fever, persistent sore throat), severe stomach/abdominal pain, persistent nausea/vomiting, vomit that looks like coffee grounds, dark urine, yellowing of the eyes/skin, easy bruising/bleeding.

    This medication may lead to high levels of potassium, especially in patients with kidney problems. If not treated, very high potassium levels can be fatal. Tell your doctor right away if you notice any of the following serious side effects: slow/irregular heartbeat, muscle weakness.

    A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

    This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

    In the US -

    Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

    In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

    Precautions

    Before taking spironolactone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

    Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney problems, liver problems, untreated mineral imbalance (such as high potassium, low sodium), decreased adrenal gland function (Addison's disease).

    Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

    This medication may increase your potassium levels. Before using potassium supplements or salt substitutes that contain potassium, consult your doctor or pharmacist. Limit foods high in potassium such as bananas, tomatoes, potatoes, and low-salt milk. Consult your doctor or pharmacist for more details, including recommendations.

    This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

    Older adults may be more sensitive to the side effects of this drug, especially the effects on potassium (see Side Effects section).

    This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.

    This medication passes into breast milk but is unlikely to harm a nursing infant. Consult your doctor before breast-feeding.

    Interactions

    See also Precautions section.

    Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

    Some products that may interact with this drug include: lithium, drugs that may increase the level of potassium in the blood (such as amiloride, cyclosporine, eplerenone, tacrolimus, triamterene, birth control pills containing drospirenone).

    Some products have ingredients that could raise your blood pressure or worsen your swelling. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen).

    This medication may interfere with certain laboratory tests (including digoxin or cortisol levels), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

    Overdose

    If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

    Notes

    Do not share this medication with others.

    Laboratory and/or medical tests (such as kidney/liver function, blood mineral levels such as potassium) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

    If you are taking this medication for high blood pressure, lifestyle changes such as stress reduction programs, exercise, and dietary changes may increase the effectiveness of this medicine. Talk to your doctor or pharmacist about lifestyle changes that might benefit you.

    Have your blood pressure checked regularly while taking this medication. Discuss with your doctor and learn how to monitor your own blood pressure. Inform your doctor of your blood pressure readings.

    Missed Dose

    If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip themissed dose and resume your usual dosing schedule. Do not double the dose to catch up.

    Storage

    Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

    Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.Information last revised August 2017. Copyright(c) 2017 First Databank, Inc.

    Images

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    spironolactone 25 mg tablet
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    M 146
    spironolactone 50 mg tablet
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    spironolactone 100 mg tablet
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    spironolactone 25 mg tablet
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    spironolactone 50 mg tablet
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    spironolactone 25 mg tablet
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    GG 85
    spironolactone 25 mg tablet
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    AN 511
    spironolactone 25 mg tablet
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    MP 35
    spironolactone 50 mg tablet
    spironolactone 50 mg tablet
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    MP 542
    spironolactone 100 mg tablet
    spironolactone 100 mg tablet
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    MP 303
    spironolactone 50 mg tablet
    spironolactone 50 mg tablet
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    AN 514
    spironolactone 100 mg tablet
    spironolactone 100 mg tablet
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    AN 515
    spironolactone 25 mg tablet
    spironolactone 25 mg tablet
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    TL 216
    spironolactone 50 mg tablet
    spironolactone 50 mg tablet
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    TL 217
    spironolactone 100 mg tablet
    spironolactone 100 mg tablet
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    TL 218
    spironolactone 25 mg tablet
    spironolactone 25 mg tablet
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    spironolactone 50 mg tablet
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    G, 5012
    spironolactone 100 mg tablet
    spironolactone 100 mg tablet
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    G, 5013
    spironolactone 25 mg tablet
    spironolactone 25 mg tablet
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    color
    white
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    round
    imprint
    MP 35
    spironolactone 25 mg tablet
    spironolactone 25 mg tablet
    View Larger Picture
    color
    white
    shape
    round
    imprint
    5880, V
    spironolactone 50 mg tablet
    spironolactone 50 mg tablet
    View Larger Picture
    color
    white
    shape
    round
    imprint
    MP 542
    spironolactone 50 mg tablet
    spironolactone 50 mg tablet
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    color
    white
    shape
    oval
    imprint
    V, 58 81
    spironolactone 100 mg tablet
    spironolactone 100 mg tablet
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    color
    white
    shape
    oval
    imprint
    MP 303
    spironolactone 100 mg tablet
    spironolactone 100 mg tablet
    View Larger Picture
    color
    white
    shape
    round
    imprint
    58 82, V
    spironolactone 50 mg tablet
    spironolactone 50 mg tablet

    Identification

    color
    white
    shape
    round
    imprint
    M 243
    This medicine is a white, round, scored, film-coated, tablet imprinted with "M 243".
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    spironolactone 100 mg tablet

    Identification

    color
    white
    shape
    round
    imprint
    M 437
    This medicine is a white, round, scored, film-coated, tablet imprinted with "M 437".
    spironolactone 25 mg tablet
    spironolactone 25 mg tablet

    Identification

    color
    white
    shape
    round
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    M 146
    This medicine is a white, round, film-coated, tablet imprinted with "M 146".
    spironolactone 50 mg tablet
    spironolactone 50 mg tablet

    Identification

    color
    white
    shape
    oval
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    logo and 672
    This medicine is a white, oval, partially scored, film-coated, tablet imprinted with "logo and 672".
    spironolactone 100 mg tablet
    spironolactone 100 mg tablet

    Identification

    color
    white
    shape
    round
    imprint
    logo 673
    This medicine is a white, round, scored, film-coated, tablet imprinted with "logo 673".
    spironolactone 25 mg tablet
    spironolactone 25 mg tablet

    Identification

    color
    white
    shape
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    803, R
    This medicine is a white, round, film-coated, tablet imprinted with "803" and "R".
    spironolactone 25 mg tablet
    spironolactone 25 mg tablet

    Identification

    color
    white
    shape
    round
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    5880, V
    This medicine is a white, round, film-coated, tablet imprinted with "5880" and "V".
    spironolactone 50 mg tablet
    spironolactone 50 mg tablet

    Identification

    color
    white
    shape
    oval
    imprint
    V, 58 81
    This medicine is a white, oval, scored, film-coated, tablet imprinted with "V" and "58 81".
    spironolactone 100 mg tablet
    spironolactone 100 mg tablet

    Identification

    color
    white
    shape
    round
    imprint
    58 82, V
    This medicine is a white, round, scored, film-coated, tablet imprinted with "58 82" and "V".
    spironolactone 25 mg tablet
    spironolactone 25 mg tablet

    Identification

    color
    white
    shape
    round
    imprint
    GG 85
    This medicine is a white, round, scored, tablet imprinted with "GG 85".
    spironolactone 25 mg tablet
    spironolactone 25 mg tablet

    Identification

    color
    white
    shape
    round
    imprint
    AN 511
    This medicine is a white, round, film-coated, tablet imprinted with "AN 511".
    spironolactone 25 mg tablet
    spironolactone 25 mg tablet

    Identification

    color
    white
    shape
    round
    imprint
    MP 35
    This medicine is a white, round, peppermint, tablet imprinted with "MP 35".
    spironolactone 50 mg tablet
    spironolactone 50 mg tablet

    Identification

    color
    white
    shape
    round
    imprint
    MP 542
    This medicine is a white, round, scored, film-coated, peppermint, tablet imprinted with "MP 542".
    spironolactone 100 mg tablet
    spironolactone 100 mg tablet

    Identification

    color
    white
    shape
    oval
    imprint
    MP 303
    This medicine is a white, oval, scored, film-coated, peppermint, tablet imprinted with "MP 303".
    spironolactone 50 mg tablet
    spironolactone 50 mg tablet

    Identification

    color
    yellow
    shape
    round
    imprint
    AN 514
    This medicine is a yellow, round, scored, film-coated, tablet imprinted with "AN 514".
    spironolactone 100 mg tablet
    spironolactone 100 mg tablet

    Identification

    color
    beige
    shape
    round
    imprint
    AN 515
    This medicine is a beige, round, scored, film-coated, tablet imprinted with "AN 515".
    spironolactone 25 mg tablet
    spironolactone 25 mg tablet

    Identification

    color
    brown
    shape
    round
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    TL 216
    This medicine is a brown, round, film-coated, tablet imprinted with "TL 216".
    spironolactone 50 mg tablet
    spironolactone 50 mg tablet

    Identification

    color
    brown
    shape
    round
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    TL 217
    This medicine is a brown, round, scored, film-coated, tablet imprinted with "TL 217".
    spironolactone 100 mg tablet
    spironolactone 100 mg tablet

    Identification

    color
    brown
    shape
    round
    imprint
    TL 218
    This medicine is a brown, round, scored, film-coated, tablet imprinted with "TL 218".
    spironolactone 25 mg tablet
    spironolactone 25 mg tablet

    Identification

    color
    light yellow
    shape
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    G, 5011
    This medicine is a light yellow, round, film-coated, tablet imprinted with "G" and "5011".
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    spironolactone 50 mg tablet

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    color
    light orange
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    G, 5012
    This medicine is a light orange, oval, scored, film-coated, tablet imprinted with "G" and "5012".
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    spironolactone 100 mg tablet

    Identification

    color
    peach
    shape
    round
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    G, 5013
    This medicine is a peach, round, scored, film-coated, tablet imprinted with "G" and "5013".
    spironolactone 25 mg tablet
    spironolactone 25 mg tablet

    Identification

    color
    white
    shape
    round
    imprint
    MP 35
    This medicine is a white, round, peppermint, tablet imprinted with "MP 35".
    spironolactone 25 mg tablet
    spironolactone 25 mg tablet

    Identification

    color
    white
    shape
    round
    imprint
    5880, V
    This medicine is a white, round, film-coated, tablet imprinted with "5880" and "V".
    spironolactone 50 mg tablet
    spironolactone 50 mg tablet

    Identification

    color
    white
    shape
    round
    imprint
    MP 542
    This medicine is a white, round, scored, film-coated, peppermint, tablet imprinted with "MP 542".
    spironolactone 50 mg tablet
    spironolactone 50 mg tablet

    Identification

    color
    white
    shape
    oval
    imprint
    V, 58 81
    This medicine is a white, oval, scored, film-coated, tablet imprinted with "V" and "58 81".
    spironolactone 100 mg tablet
    spironolactone 100 mg tablet

    Identification

    color
    white
    shape
    oval
    imprint
    MP 303
    This medicine is a white, oval, scored, film-coated, peppermint, tablet imprinted with "MP 303".
    spironolactone 100 mg tablet
    spironolactone 100 mg tablet

    Identification

    color
    white
    shape
    round
    imprint
    58 82, V
    This medicine is a white, round, scored, film-coated, tablet imprinted with "58 82" and "V".

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    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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