DIOSMIN Overview Information
Diosmin is a type of plant chemical found mainly in citrus fruits. People use diosmin to make medicine.
Diosmin is used for treating various disorders of blood vessels including hemorrhoids, varicose veins, poor circulation in the legs (venous stasis), and bleeding (hemorrhage) in the eye or gums. It is also used to treat swelling of the arms (lymphedema) following breast cancer surgery, and to protect against liver toxicity. It is often taken in combination with hesperidin, another plant chemical.
How does it work?
Possibly Effective for:
- Hemorrhoids. Taking diosmin in high doses along with hesperidin seems to reduce symptoms of hemorrhoids. Taking diosmin in lower doses along with hesperidin plus troxerutin or along with bulk laxatives also seems to reduce symptoms. Taking diosmin in lower doses along with hesperidin seems to help prevent recurrence.
- Leg ulcers caused by poor circulation.. Taking diosmin in combination with hesperidin and compression dressing seems to help heal leg ulcers caused by poor circulation.
Possibly Ineffective for:
- Swelling of the arms (lymphedema) following surgery for breast cancer. Taking diosmin along with hesperidin does not reduce swelling of the arms following surgery for breast cancer.
- Bleeding gums.
- Bleeding (hemorrhage) in the eye.
- Preventing damage to the liver.
- Varicose veins.
- Other conditions.
DIOSMIN Side Effects & Safety
Diosmin is safe for most people when used short-term for up to 6 months. It can cause some side effects such as stomach and abdominal pain, diarrhea, dizziness, headache, skin redness and hives, muscle pain, blood problems, and altered heart rate.
Special Precautions & Warnings:Pregnancy and breast-feeding: Not enough is known about the use of diosmin during pregnancy and breast-feeding. Stay on the safe side and avoid use.
Bleeding disorders: Diosmin might make bleeding disorders worse. If you have a bleeding disorder, don't use diosmin.
Diosmin is often taken in combination with hesperidin.
The following doses have been studied in scientific research:
- For hemorrhoids: For treating hemorrhoids, 1350 mg of diosmin plus 150 mg of hesperidin twice daily for 4 days followed by 900 mg of diosmin and 100 mg of hesperidin twice daily for 3 days has been used. Also, 300 mg of diosmin, 300 mg of troxerutin, and 300 mg of hesperidin three times daily for 3 days, followed by two times daily for 2 days, and then once daily for 7 days has been used. Thereafter, 300 mg of diosmin, 300 mg of troxerutin, and 100 mg of hesperidin has been used daily for one month (93885). Some researchers also try 600 mg of diosmin three times daily for 4 days, followed by 300 mg twice daily for 10 days, in combination with 11 grams of psyllium daily. However, this lower diosmin dose does not seem to be as effective.
- For leg ulcers caused by poor circulation (venous stasis ulcers): 900 mg of diosmin plus 100 mg of hesperidin daily has been used for up to 2 months.