NADH stands for "nicotinamide adenine dinucleotide (NAD) + hydrogen (H)." It occurs naturally in the body and plays a role in generating energy.

The NADH produced by the body is involved in making energy in the body. Taking NADH supplements might affect blood pressure and have other effects.

People use NADH for chronic fatigue syndrome (CFS), high blood pressure, high cholesterol, athletic performance, depression, Parkinson disease, and many other conditions, but there is no good scientific evidence to support these uses.

Don't confuse NADH with niacin, niacinamide, or nicotinamide riboside. These are not the same.

Uses & Effectiveness ?

Possibly Effective for

  • Chronic fatigue syndrome (CFS). Taking NADH by mouth, alone or together with coenzyme Q10, might somewhat reduce symptoms of CFS.
There is interest in using NADH for a number of other purposes, but there isn't enough reliable information to say whether it might be helpful.

Side Effects

When taken by mouth: NADH is possibly safe for most people when used for up to 12 weeks. It's usually well-tolerated.

Special Precautions and Warnings

When taken by mouth: NADH is possibly safe for most people when used for up to 12 weeks. It's usually well-tolerated.

Pregnancy and breast-feeding: There isn't enough reliable information to know if NADH is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Interactions ?

We currently have no information for NADH overview.


NADH has most often been used by adults in doses of 5-10 mg by mouth daily for up to 24 months. Speak with a healthcare provider to find out what dose might be best for a specific condition.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

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© Therapeutic Research Faculty 2020.