CALIFORNIA POPPY

OTHER NAME(S):

Amapola de California, Eschscholzia californica, Pavot d’Amérique, Pavot d’Or, Pavot de Californie, Poppy California, Yellow Poppy.<br/><br/>

Overview

Overview Information

California poppy is a plant. It is the state flower of California. People use the parts that grow above the ground for medicine.

California poppy is used for trouble sleeping (insomnia), aches, nervous agitation, bed-wetting in children, and diseases of the bladder and liver. It is also used to promote relaxation.

In combination with other herbs, California poppy is used for depression, long-term mental and physical tiredness (neurasthenia), nerve pain, various psychiatric conditions, blood vessel problems, sensitivity to weather changes, and sedation. An herb combination including California poppy is also used for sleep and mood disturbance associated with strong, warm wind in the Alps (foehn illness).

How does it work?

California poppy contains chemicals that might cause relaxation and sleepiness.

Uses

Uses & Effectiveness?

Insufficient Evidence for

  • Anxiety. Developing research suggests California poppy, in combination with magnesium and hawthorn, might be useful in treating mild-to-moderate anxiety disorders. This combination product, called Sympathyl, is not available in the US.
  • Trouble sleeping (insomnia).
  • Aches.
  • Bed-wetting.
  • Diseases of the bladder.
  • Diseases of the liver.
  • Other conditions.
More evidence is needed to rate the effectiveness of California poppy for these uses.

Side Effects

Side Effects & Safety

California poppy appears to be safe for most people when taken appropriately by mouth for three months or less. There isn't enough information to know if California poppy is safe for longer term use.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Not enough is known about the use of California poppy during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Surgery: California poppy can slow down the central nervous system, causing sleepiness and other effects. There is some concern that California poppy might slow down the central nervous system too much when combined with anesthesia and other medications used during and after surgery. Stop using California poppy at least 2 weeks before a scheduled surgery.

Interactions

Interactions?

Moderate Interaction

Be cautious with this combination

!
  • Sedative medications (Benzodiazepines) interacts with CALIFORNIA POPPY

    California poppy might cause sleepiness and drowsiness. Drugs that cause sleepiness and drowsiness are called sedatives. Taking California poppy along with sedative medications might cause too much sleepiness.<br /> Some of these sedative medications include clonazepam (Klonopin), diazepam (Valium), lorazepam (Ativan), and others.

  • Sedative medications (CNS depressants) interacts with CALIFORNIA POPPY

    California poppy might cause sleepiness and drowsiness. Medications that cause sleepiness are called sedatives. Taking California poppy along with sedative medications might cause too much sleepiness.<br /> Some sedative medications include clonazepam (Klonopin), lorazepam (Ativan), phenobarbital (Donnatal), zolpidem (Ambien), and others.

Dosing

Dosing

The appropriate dose of California poppy depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for California poppy. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References

REFERENCES:

  • Xu, L. F., Wang, M., and Zhao, C. L. [Clinical effects and experimental study on gossypol in endometriosis]. Zhong.Xi.Yi.Jie.He.Za Zhi. 1989;9(8):462-4, 451. View abstract.
  • Xue, S. [A beam of dawn light of study on gossypol as a safe, effective, and reversible male antifertility contraceptive--evaluation of the studies by using low dose gossypol combined with steroid hormone for male contraception]. Zhongguo Yi.Xue.Ke.Xue.Yuan Xue.Bao. 2000;22(3):211-213. View abstract.
  • Xue, S. P., Liang, D. C., Fei, R. R., Chen, X. M., Ye, S. J., Liu, Y., Wu, Y. W., You, M. M., and Guo, X. Y. Subcellular site of antispermatogenic effect of gossypol and its possible molecular mechanism of action. Sci.Sin.[B] 1983;26(6):614-633. View abstract.
  • Yang, B., Cao, L., Xu, Y., Sun, Z. X., and Gu, Z. P. [The effects of gossypol on rat luteal cells, human decidual cells and cytotrophoblasts]. Yao Xue.Xue.Bao. 1997;32(8):573-577. View abstract.
  • Ye, W. S., Lang, J. C., and Hsu, T. C. [Clastogenicity of a male contraceptive, gossypol, in mammalian cell cultures with and without metabolic activation by S9 mix]. Zhongguo Yi.Xue.Ke.Xue.Yuan Xue.Bao. 1986;8(2):100-105. View abstract.
  • Ye, W. S., Liang, J. C., and Hsu, T. C. Toxicity of a male contraceptive, gossypol, in mammalian cell cultures. In Vitro 1983;19(1):53-57. View abstract.
  • Gafner, S., Dietz, B. M., McPhail, K. L., Scott, I. M., Glinski, J. A., Russell, F. E., McCollom, M. M., Budzinski, J. W., Foster, B. C., Bergeron, C., Rhyu, M. R., and Bolton, J. L. Alkaloids from Eschscholzia californica and their capacity to inhibit binding of [3H]8-Hydroxy-2-(di-N-propylamino)tetralin to 5-HT1A receptors in Vitro. J Nat Prod. 2006;69(3):432-435. View abstract.
  • Hanus M, Lafon J, Mathieu M. Double-blind, randomised, placebo-controlled study to evaluate the efficacy and safety of a fixed combination containing two plant extracts (Crataegus oxyacantha and Eschscholtzia californica) and magnesium in mild-to-moderate anxiety disorders. Curr Med Res Opin 2004;20:63-71. View abstract.
  • Paul LD, Maurer HH. Studies on the metabolism and toxicological detection of the Eschscholtzia californica alkaloids californine and protopine in urine using gas chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2003;789:43-57. View abstract.
  • Paul LD, Springer D, Staack RF, et al. Cytochrome P450 isoenzymes involved in rat liver microsomal metabolism of californine and protopine. Eur J Pharmacol 2004;485:69-79. View abstract.
  • Rolland A, Fleurentin J, Lanhers MC, et al. Behavioural effects of the American traditional plant Eschscholzia californica: sedative and anxiolytic properties. Planta Med 1991;57:212-6. View abstract.
  • Rolland A, Fleurentin J, Lanhers MC, et al. Neurophysiological effects of an extract of Eschscholzia californica Cham. (Papaveraceae). Phytother Res 2001;15:377-81. View abstract.

More Resources for CALIFORNIA POPPY

CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
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